Death signals
Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia – Kinga Duszyc, Jessica B. von Pein, Divya Ramnath, Denni Currin-Ross, Suzie Verma, Fayth Lim, Matthew J. Sweet, Kate Schroder, Alpha S. Yap. https://www.cell.com/developmental-cell/fulltext/S1534-5807(23)00405-7
Apoptotic signaling clears engineered Salmonella in an organ-specific manner – Taylor J. Abele, Zachary P. Billman, Lupeng Li, Carissa K. Harvest, Alexia K. Bryan, Gabrielle R Magalsk, iJoseph P Lopez, Heather N. Larson, Xiao-Ming Yin, Edward A. Miao. https://elifesciences.org/reviewed-preprints/89210
Caspases and cFLIP
cFLIPL acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes – Pavel Davidovich, Catherine A. Higgins, Zaneta Najda, Daniel B. Longley, Seamus J. Martin. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01488-2
Bcl-2 family proteins
Apoptotic dysregulation mediates stem cell competition and tissue regeneration – Marianna Yusupova, Roi Ankawa, Yahav Yosefzon, David Meiri, Ido Bachelet and Yaron Fuchs. https://www.cell.com/current-biology/fulltext/S0960-9822(23)01298-8
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies – Stephen Jun Fei Chong, Fen Zhu, Olga Dashevsky, Rin Mizuno, Jolin X.H. Lai, Liam Hackett, Christine E. Ryan, Mary C. Collins, J. Bryan Iorgulescu, Romain Guièze, Johany Penailillo, Ruben Carrasco, Yeonjoo C. Hwang, Denise P. Muñoz, Mehdi Bouhaddou, Yaw Chyn Lim, Catherine J. Wu, John N. Allan, Richard R. Furman, Boon Cher Goh, Shazib Pervaiz, Jean-Philippe Coppé, Constantine S. Mitsiades, and Matthew S. Davids. https://www.jci.org/articles/view/170169
A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation – Mary Speir, Hazel Tye, Timothy A Gottschalk, Daniel S Simpson, Tirta M Djajawi, Pankaj Deo, Rebecca L Ambrose, Stephanie A Conos, Jack Emery, Gilu Abraham, Ashlyn Pascoe, Sebastian A Hughes, Ashley Weir, Edwin D Hawkins, Isabella Kong, Marco J Herold, Jaclyn S Pearson, Najoua Lalaoui, Thomas Naderer, James E Vince, Kate E Lawlor. https://www.embopress.org/doi/full/10.15252/embr.202356865
Death receptors/IAPs
cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation – Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars M Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas, Domagoj Vucic, John Silke, Manolis Pasparakis, Hamid Kashkar. https://www.embopress.org/doi/full/10.15252/embj.2023113614
Characterizing the regulatory Fas (CD95) epitope critical for agonist antibody targeting and CAR-T bystander function in ovarian cancer – Tanmoy Mondal, Himanshu Gaur, Brice E. N. Wamba, Abby Grace Michalak, Camryn Stout, Matthew R. Watson, Sophia L. Aleixo, Arjun Singh, Salvatore Condello, Roland Faller, Gary Scott Leiserowitz, Sanchita Bhatnagar and Jogender Tushir-Singh. https://www.nature.com/articles/s41418-023-01229-7
Necrosis / necroptosis
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis – Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele and Mathieu J. M. Bertrand. https://www.nature.com/articles/s41419-023-06284-z
Triggering endogenous Z-RNA sensing for anti-tumor therapy through ZBP1-dependent necroptosis – Tao Yang, Guodong Wang, Mingxiang Zhang, Xiaohu Hu, Qi Li, Fenglin Yun, Yingying Xing, Xinyang Song, Haibing Zhang, Guohong Hu, Youcun Qian. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01389-X
Pyroptosis
Caspase-1 activates gasdermin A in all non-mammals – Zachary P. Billman, Stephen B. Kovacs, Bo Wei, Kidong Kang, Ousmane H. Cissé, Edward A. Miao. https://elifesciences.org/reviewed-preprints/92362
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis – Rui Miao, Cong Jiang, Winston Y. Chang, Haiwei Zhang, Jinsu An, Felicia Ho, Pengcheng Chen, Han Zhang, Caroline Junqueira, Dulguun Amgalan, Felix G. Liang, Junbing Zhang, Charles L. Evavold, Iva Hafner-Bratkovič, Zhibin Zhang, Pietro Fontana, Shiyu Xia, Markus Waldeck-Weiermair, Youdong Pan, Thomas Michel, Liron Bar-Peled, Hao Wu, Jonathan C. Kagan, Richard N. Kitsis, Peng Zhang, Xing Liu, Judy Lieberman. https://www.cell.com/immunity/fulltext/S1074-7613(23)00444-2
Cytotoxicity
Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis – Arianne C Richard, Claire Y Ma, John C Marioni, Gillian M Griffiths. https://www.embopress.org/doi/full/10.15252/embr.202357653
Miscellanous
Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration – Qinghao Yu, Hannah E. Walters, Giovanni Pasquini, Sumeet Pal Singh, Martina Lachnit, Catarina R. Oliveira, Daniel León-Periñán, Andreas Petzold, Preethi Kesavan, Cristina Subiran Adrados, Ines Garteizgogeascoa, Dunja Knapp, Anne Wagner, Andrea Bernardos, María Alfonso, Gayathri Nadar, Alwin M. Graf, Konstantin E. Troyanovskiy, Andreas Dahl, Volker Busskamp, Ramón Martínez-Máñez, Maximina H. Yun. https://www.cell.com/developmental-cell/fulltext/S1534-5807(23)00510-5
Epithelial apoptotic pattern emerges from global and local regulation by cell apical area – Victoire M.L. Cachoux, Maria Balakireva, Mélanie Gracia, Floris Bosveld, Jesús M. López-Gay, Aude Maugarny, Isabelle Gaugué, Florencia di Pietro, Stéphane U. Rigaud, Lorette Noiret, Boris Guirao, Yohanns Bellaïche. https://www.cell.com/current-biology/fulltext/S0960-9822(23)01298-8
Reviews
Ferroptosis: mechanisms and implications for cancer development and therapy response – Ancély Ferreira dos Santos, Gholamreza Fazeli, Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli. https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00079-X
Regulation of ferroptosis by lipid metabolism – Lauren E. Pope, Scott J. Dixon. https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00086-7
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis – Jihye Yang, Yoontae Lee, Cheol-Sang Hwang. https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00136-8
Comments
Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2 – Seamus J. Martin. https://www.cell.com/trends/immunology/fulltext/S1471-4906(23)00203-X
Enhancing dendritic cells by inhibiting BCL2 – Christopher A.G. Booth, Andrew A. Lane. https://www.cell.com/trends/cancer/fulltext/S2405-8033(23)00191-7
Senescent cells support limb regeneration – Paulina Strzyz. https://www.nature.com/articles/s41580-023-00684-x
Epithelial homeostasis: Cell size shapes cell fate – Xiang Teng, Yusuke Toyama. https://www.cell.com/current-biology/fulltext/S0960-9822(23)01408-2
Proinflammatory apoptosis – BY ANNALISA M. VANHOOK. https://www.science.org/doi/10.1126/scisignal.adm8181
Apoptosis and cell death 