Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for June, 2018

ApoList – May 2018

Posted by cris on June 1, 2018

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Bcl-2 family proteins
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Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK
Francine F.S. Ke, Hannah K. Vanyai, Angus D. Cowan, Alex R.D. Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E. Czabotar, Anne K. Voss, Andreas Strasser
https://www.cell.com/cell/fulltext/S0092-8674(18)30567-1

Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis
Janet H. Zheng, Christy R. Grace, Cristina D. Guibao, Dan E. McNamara, Fabien Llambi, Yue-Ming Wang, Taosheng Chen, Tudor Moldoveanu
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30619-3

Analysis of neuronal phosphoproteome reveals PINK1 regulation of BAD function and cell death
Huida Wan, Bin Tang, Xun Liao, Qiufang Zeng, Zhuohua Zhang & Lujian Liao
https://www.nature.com/articles/s41418-017-0027-x

Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
Álvaro F. Fernández, Salwa Sebti, Yongjie Wei, Zhongju Zou, Mingjun Shi, Kathryn L. McMillan, Congcong He, Tabitha Ting, Yang Liu, Wei-Chung Chiang, Denise K. Marciano, Gabriele G. Schiattarella, Govind Bhagat, Orson W. Moe, Ming Chang Hu & Beth Levine
https://www.nature.com/articles/s41586-018-0162-7

BCL2 AND BCL(X)L SELECTIVE INHIBITORS DECREASE MITOCHONDRIAL ATP PRODUCTION IN BREAST CANCER CELLS AND ARE SYNTHETICALLY LETHAL WHEN COMBINED WITH 2-DEOXY-D-GLUCOSE
Federico Lucantoni, Heiko Düssmann, Irene Llorente-Folch, and Jochen H.M. Prehn
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=25433&path%5B%5D=79650

INDUCTION OF APOPTOSIS AND SUPPRESSION OF TUMOR GROWTH BY NUR77-DERIVED BCL-2 CONVERTING PEPTIDE IN CHEMORESISTANT LUNG CANCER CELLS
Martin C. Pearce, John T. Gamble, Prasad R. Kopparapu, Edmond F. O’Donnell, Monica J. Mueller, Hyo Sang Jang,Julie A. Greenwood, Arnold C. Satterthwait, Roberta L. Tanguay, Xiao-Kun Zhang,  and  Siva Kumar Kolluri
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=25437&path%5B%5D=79662

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility
Quynh-Nhu Nguyen, Nadeen Zerafa, Seng H. Liew, F. Hamish Morgan, Andreas Strasser, Clare L. Scott, Jock K. Findlay, Martha Hickey & Karla J. Hutt
https://www.nature.com/articles/s41419-018-0633-7

Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells
Mohamed Rahmani, Jewel Nkwocha, Elisa Hawkins, Xinyan Pei, Rebecca E. Parker, Maciej Kmieciak, Joel D. Leverson, Deepak Sampath, Andrea Ferreira-Gonzalez and Steven Grant
http://cancerres.aacrjournals.org/content/78/11/3075

Bcl-2 Protein Targeting by the p53/p21 Complex—Letter
Liz J. Hernandez Borrero, Rahmat Sikder, Amriti Lulla, Prashanth Gokare, Paulo R. Del Valle, Xiaobing Tian, Shengliang Zhang, Philip H. Abbosh and Wafik S. El-Deiry
http://cancerres.aacrjournals.org/content/78/10/2770

Bcl-2 Protein Targeting by the p53/p21 Complex—Response
Eun Mi Kim, Jongdoo Kim and Hong-Duck Um
http://cancerres.aacrjournals.org/content/78/10/2772

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Death receptors and IAPs
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N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
Yann Estornes, Yves Dondelinger, Kathrin Weber, Inge Bruggeman, Adam Peall, Marion MacFarlane, Serge Lebecque, Peter Vandenabeele & Mathieu J. M. Bertrand
https://www.nature.com/articles/s41419-018-0544-7

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes
Sylwia Gradzka, Oliver S. Thomas, Oliver Kretz, Aladin Haimovici, Lazaros. Vasilikos, Wendy Wei-Lynn Wong, Georg Häcker & Ian E. Gentle
https://www.nature.com/articles/s41419-018-0508-y

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Caspases
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Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size
Yahav Yosefzon, Despina Soteriou, Alona Feldman, Lana Kostic, Elle Koren, Samara Brown, Roi Ankawa, Egor Sedov, Fabian Glaser, Yaron Fuchs
https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30315-0

Plasma Membrane Localization of Apoptotic Caspases for Non-apoptotic Functions
Alla Amcheslavsky, Shiuan Wang, Caitlin E. Fogarty, Jillian L. Lindblad, Yun Fan, Andreas Bergmann
https://www.cell.com/developmental-cell/fulltext/S1534-5807(18)30326-5

Balance between senescence and apoptosis is regulated by telomere damage–induced association between p16 and caspase-3
Shanmugam Panneer Selvam, Braden M Roth, Rose Nganga, Jisun Kim, Marion A Cooley, Kristi L. Helke, Charles D. Smith and Besim Ogretmen
http://www.jbc.org/content/early/2018/05/10/jbc.RA118.003506.abstract

Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation
Na Shang, Thomas Bank, Xianzhong Ding, Peter Breslin, Jun Li, Baomin Shi & Wei Qiu
https://www.nature.com/articles/s41419-018-0617-7

Caspase-mediated cleavage of the centrosomal proteins during apoptosis
Mi Young Seo & Kunsoo Rhee
https://www.nature.com/articles/s41419-018-0632-8

Mutations in the P10 region of procaspase-8 lead to chemotherapy resistance in acute myeloid leukemia by impairing procaspase-8 dimerization
Ming Li, Xiao-Mo Wu, Ju Gao, Fen Yang, Cui-Lin Zhang, Kun Ke, Ying-Chao Wang, You-Shi Zheng, Jian-Feng Yao, Ying-Ying Guan, Xuan Chen, Juan Chen, Xiao-Long Liu & Xiao-Yu Yang
https://www.nature.com/articles/s41419-018-0511-3

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RIK1 / Necroptosis
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The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex
Miguel Mompeán, Wenbo Li, Jixi Li, Ségolène Laage, Ansgar B. Siemer, Gunes Bozkurt, Hao Wu, Ann E. McDermott
https://www.cell.com/cell/fulltext/S0092-8674(18)30312-X

RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis
Fanxin Zeng, Xiao Chen, Weiyi Cui, Wei Wen, Fujian Lu, Xueting Sun, Dongwei Ma, Ye Yuan, Zezhong Li, Ning Hou, Hong Zhao, Xinyu Bi, Jianjun Zhao, Jianguo Zhou, Yan Zhang, Rui-Ping Xiao, Jianqiang Cai and Xiuqin Zhang
http://cancerres.aacrjournals.org/content/78/11/2876

Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis
Norah A. Alturki, Scott McComb, Ardeshir Ariana, Dikchha Rijal, Robert G. Korneluk, Shao-Cong Sun, Emad Alnemri & Subash Sad
https://www.nature.com/articles/s41419-018-0672-0

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Efferocytosis / immunogenicity
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NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages
Juhi Bagaitkar, Jing Huang, Melody Yue Zeng, Nancy K. Pech, Darlene A. Monlish, Lizet J. Perez-Zapata, Irina Miralda, Laura G. Schuettpelz and
Mary C. Dinauer
http://bloodjournal.org/content/131/21/2367.abstract?etoc

Repeated Exposure of Epithelial Cells to Apoptotic Cells Induces the Specific Selection of an Adaptive Phenotype: Implications for Tumorigenesis
Lanfei Feng, Snezana Vujicic, Michael E Dietrich, Natalia Litbarg, Suman Setty, Angelika Antoni, Joyce Rauch and Jerrold S Levine
http://www.jbc.org/content/early/2018/05/16/jbc.RA117.001290.abstract

Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
Rahul Shinde  Kebria Hezaveh, Marie Jo Halaby, Andreas Kloetgen, Ankur Chakravarthy, Tiago da Silva Medina, Reema Deol, Kieran P. Manion, Yuriy Baglaenko, Maria Eldh, Sara Lamorte, Drew Wallace, Sathi Babu Chodisetti, Buvana Ravishankar, Haiyun Liu, Kapil Chaudhary, David H. Munn, Aristotelis Tsirigos, Michael Madaio, Susanne Gabrielsson, Zahi Touma, Joan Wither, Daniel D. De Carvalho & Tracy L. McGaha
http://www.nature.com/articles/s41590-018-0107-1

Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
Jeonghyun Ahn, Tianli Xia, Ailem Rabasa Capote, Dillon Betancourt, Glen N. Barber
https://www.cell.com/cancer-cell/fulltext/S1535-6108(18)30132-6

C. elegans Blastomeres Clear the Corpse of the Second Polar Body by LC3-Associated Phagocytosis
Gholamreza Fazeli, Maurice Stetter, Jaime N. Lisack, Ann M. Wehman
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30587-4


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Miscellaneous

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PNPT1 Release from Mitochondria during Apoptosis Triggers Decay of Poly(A) RNAs
Xing Liu, Rui Fu4, Youdong Pan, Karla F. Meza-Sosa, Zhibin Zhang, Judy Lieberman
https://www-cell-com/cell/fulltext/S0092-8674(18)30510-5

Neutrophil extracellular traps promote macrophage pyroptosis in sepsis
Linsong Chen, Yanfeng Zhao, Dengming Lai, Peng Zhang, Yang Yang, Yuehua Li, Ke Fei, Gening Jiang & Jie Fan
https://www.nature.com/articles/s41419-018-0538-5

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Reviews
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Radiation-Induced Cardiovascular Toxicity: Mechanisms, Prevention, and Treatment
Johan Spetz, Javid Moslehi, Kristopher Sarosiek
https://link.springer.com/article/10.1007/s11936-018-0627-x

Regulation of lipid peroxidation and ferroptosis in diverse species
Marcus Conrad, Valerian E. Kagan, Hülya Bayir, Gabriela C. Pagnussat,  Brian Head, Maret G. Traber and Brent R. Stockwell
http://genesdev.cshlp.org/content/32/9-10/602.abstract?etoc

Apoptotic Caspases: Multiple or Mistaken Identities?
Kate McArthur, Benjamin T. Kile
https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(18)30027-8

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Comments
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Better Together: A Hybrid Amyloid Signals Necroptosis
Dan Li, Cong Liu
https://www.cell.com/cell/fulltext/S0092-8674(18)30523-3

RIP3 is an upregulator of aerobic metabolism and the enhanced respiration by necrosomal RIP3 feeds back on necrosome to promote necroptosis
Xingfeng Qiu, Yingying Zhang & Jiahuai Han
https://www.nature.com/articles/s41418-018-0075-x

How do thymic epithelial cells die?
Reema Jain, Justine D. Mintern, Iris Tan, Grant Dewson, Andreas Strasser & Daniel H. D. Gray
https://www.nature.com/articles/s41418-018-0093-8

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