Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for July, 2017

ApoList – July 2017

Posted by cris on July 31, 2017

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Necroptosis and RIP kinases
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MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
Seongmin Yoon, Andrew Kovalenko, Konstantin Bogdanov, David Wallach
http://www.cell.com/immunity/fulltext/S1074-7613(17)30228-5

Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis
Sefi Zargarian Inbar Shlomovitz , Ziv Erlich, Aria Hourizadeh, Yifat Ofir-Birin, Ben A. Croker, Neta Regev-Rudzki, Liat Edry-Botzer, Motti Gerlic
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002711

SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination
Ran Wei, Lily Wen Xu, Jianping Liu, Yanxia Li, Pei Zhang, Bing Shan, Xiaojuan Lu, Lihui Qian, Zheming Wu, Kangyun Dong, Hong Zhu, Lifeng Pan, Junying Yuan, and Heling Pan
http://genesdev.cshlp.org/content/31/11/1162.abstract?etoc

RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice
Yongbo Liu, Cunxian Fan, Yifan Zhang, Xianjun Yu, Xiaoxia Wu, Xixi Zhang, Qun Zhao, Haiwei Zhang, Qun Xie, Ming Li, Xiaoming Li, Qiurong Ding, Hao Ying, Dali Li and Haibing Zhang
http://www.nature.com/cdd/journal/v24/n8/abs/cdd201778a.html

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Non-apoptotic cell death
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Entosis Is Induced by Glucose Starvation
Jens C. Hamann, Alexandra Surcel, Ruoyao Chen, Carolyn Teragawa, John G. Albeck, Douglas N. Robinson, Michael Overholtzer
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30851-3

Mitosis can drive cell cannibalism through entosis
Joanne Durgan, Yun-Yu Tseng, Jens C Hamann, Marie-Charlotte Domart, Lucy Collinson, Alan Hall, Michael Overholtzer, Oliver Florey
https://elifesciences.org/articles/27134

Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C‐ring conformation
Massimo Bonora, Claudia Morganti, Giampaolo Morciano, Gaia Pedriali, Magdalena Lebiedzinska‐Arciszewska, Giorgio Aquila, Carlotta Giorgi, Paola Rizzo, Gianluca Campo, Roberto Ferrari, Guido Kroemer, Mariusz R Wieckowski, Lorenzo Galluzzi, and Paolo Pinton
http://EMBOr.embopress.org/content/18/7/1077?etoc

Ca^2+ binding to F‐ATP synthase β subunit triggers the mitochondrial permeability transition
Valentina Giorgio, Victoria Burchell, Marco Schiavone, Claudio Bassot, Giovanni Minervini, Valeria Petronilli, Francesco Argenton, Michael Forte, Silvio Tosatto, Giovanna Lippe, and Paolo Bernardi
http://EMBOr.embopress.org/content/18/7/1065?etoc

Live cell visualization of gasdermin D-driven pyroptotic cell death
Joseph K Rathkey, Bryan L Benson, Steven M Chirieleison, Jie Yang, Tsan S Xiao, George R Dubyak, Alex Y Huang, and Derek W Abbott
http://www.jbc.org/content/early/2017/07/18/jbc.M117.797217.abstract

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Bcl-2 family
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BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
Mark Xiang Li, Iris K. L. Tan, Stephen B. Ma, Colin Hockings, Tobias Kratina, Michael A. Dengler, Amber E. Alsop, Ruth M. Kluck, and Grant Dewson
http://www.pnas.org/content/114/29/7629.abstract

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy
Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh and Emily H. Cheng
https://www.nature.com/articles/ncomms16078

USE OF A MCL-1 INHIBITOR ALONE TO DE-BULK MELANOMA AND IN COMBINATION TO KILL MELANOMA INITIATING CELLS
Nabanita Mukherjee, Yan Lu, Adam Almeida, Karoline Lambert, Chung-Wai Shiau, Jung-Chen Su, Yuchun Luo,Mayumi Fujita, William A. Robinson, Steven E. Robinson, David A. Norris, and Yiqun G. Shellman
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=8695

BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation
Naoko Tsuyama, Seiji Sakata, Satoko Baba, Yuko Mishima, Noriko Nishimura,
Kyoko Ueda, Masahiro Yokoyama, Yasuhito Terui, Kiyohiko Hatake, Masanobu Kitagawa, Naoki Ishizuka, Naoto Tomita, and Kengo Takeuchi
http://www.bloodjournal.org/content/130/4/489

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Caspases and IAPs
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Caspase-9 has a nonapoptotic function in Xenopus embryonic primitive blood formation
Hong Thi Tran, Mathias Fransen, Dionysia Dimitrakopoulou, Griet Van Imschoot, Nicolas Willemarck, and Kris Vleminckx
http://jcs.biologists.org/content/130/14/2371

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
Kate E. Lawlor, Rebecca Feltham, Monica Yabal, Stephanie A. Conos, Kaiwen W. Chen, Stephanie Ziehe, Carina Graß, Yifan Zhan, Tan A. Nguyen, Cathrine Hall, Angelina J. Vince, Simon M. Chatfield, Damian B. D’Silva, Kenneth C. Pang, Kate Schroder, John Silke, David L. Vaux, Philipp J. Jost, James E. Vince
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30904-X

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Miscellaneous
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TIR-domain-containing adapter-inducing interferon-β (TRIF) forms filamentous structures, whose pro-apoptotic signalling is terminated by autophagy
Ian E. Gentle, Kevin T. McHenry, Arnim Weber, Arlena Metz, Oliver Kretz, Dale Porter and Georg Häcker
http://onlinelibrary.wiley.com/doi/10.1111/febs.14091/abstract

Accumulation of autophagosomes confers cytotoxicity
Robert W. Button, Sheridan L. Roberts, Thea L. Willis, C. Oliver Hanemann, and Shouqing Luo
http://www.jbc.org/content/early/2017/07/03/jbc.M117.782276.abstract

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Reviews
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Apoptosis and Cancer
Anthony Letai
http://www.annualreviews.org/doi/full/10.1146/annurev-cancerbio-050216-121933

Dysregulation of BCL-2 Family Proteins by Leukaemia Fusion Genes
Lauren M Brown, Diane T Hanna, Seong L Khaw, and Paul G Ekert
http://www.jbc.org/content/early/2017/07/17/jbc.R117.799056.abstract

The mitochondria–endoplasmic reticulum contact sites: a signalling platform for cell death
Julien Prudent, Heidi M McBride
http://www.sciencedirect.com/science/article/pii/S095506741730011X

Caspases in retinal ganglion cell death and axon regeneration
Chloe N Thomas, Martin Berry, Ann Logan, Richard J Blanch & Zubair Ahmed
http://www.nature.com/articles/cddiscovery201732


Cell Death and Differentiation special issue on non-apoptotic roles of caspases
http://www.nature.com/cdd/journal/v24/n8/index.html#Reviews

CDPs: caspase-dependent non-lethal cellular processes
Lior Aram, Keren Yacobi-Sharon and Eli Arama
http://www.nature.com/cdd/journal/v24/n8/full/cdd2017111a.html

– Metacaspases versus caspases in development and cell fate regulation
E A Minina, N S Coll, H Tuominen and P V Bozhkov
– Non-apoptotic cell death in animal development
Lena M Kutscher and Shai Shaham
– Non-apoptotic functions of caspases in myeloid cell differentiation
Stéphanie Solier, Michaela Fontenay, William Vainchenker, Nathalie Droin and Eric Solary
– Non-apoptotic functions of BCL-2 family proteins FREE
Atan Gross and Samuel G Katz
– Evolution of caspase-mediated cell death and differentiation: twins separated at birth O
Ryan A V Bell and Lynn A Megeney
– Caspase involvement in autophagy FREE
Panagiotis Tsapras and Ioannis P Nezis
– Caspases and their substrates FREE
Olivier Julien and James A Wells
– Killers creating new life: caspases drive apoptosis-induced proliferation in tissue repair and disease OPEN
Caitlin E Fogarty and Andreas Bergmann
– Viral hijacking of host caspases: an emerging category of pathogen–host interactions FREE
Patrick F Connolly and Howard O Fearnhead
– More alive than dead: non-apoptotic roles for caspases in neuronal development, plasticity and disease OPEN
Amrita Mukherjee and Darren W Williams
– Caspase-dependent non-apoptotic processes in development OPEN
Yu-ichiro Nakajima and Erina Kuranaga

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Comments
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Necroptosis: (Last) Message in a Bubble
Peter Vandenabeele, Franck Riquet, Benjamin Cappe
http://www.cell.com/immunity/fulltext/S1074-7613(17)30285-6

Autophagy regulates apoptosis on the level of the death-inducing signalling complex
Karin Nowikovsky, Michael Bergmann
http://onlinelibrary.wiley.com/doi/10.1111/febs.14119/abstract

Chemotherapy-Activated Caspase 3 Cleaves GSDME to Drive Pyroptosis
http://cancerdiscovery.aacrjournals.org/content/7/7/OF7

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ApoList – June 2017

Posted by cris on July 2, 2017

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Non-apoptotic cell death
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Complement-Related Regulates Autophagy in Neighboring Cells
Lin Lin, Frederico S.L.M. Rodrigues, Christina Kary, Alicia Contet, Mary Logan, Richard H.G. Baxter, Will Wood, Eric H. Baehrecke
http://www.cell.com/cell/fulltext/S0092-8674(17)30701-8

Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells
Shinwon Ha, Seol-Hwa Jeong, Kyungrim Yi, Kyung Min Chung, Caroline Jeeyeon Hong, Seong Who Kim, Eun-Kyoung Kim and Seong-Woon Yu
http://www.jbc.org/content/early/2017/06/27/jbc.M117.780874.abstract?papetoc

Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells
Blandine Monel, Alex A Compton, Timothée Bruel, Sonia Amraoui, Julien Burlaud‐Gaillard, Nicolas Roy, Florence Guivel‐Benhassine, Françoise Porrot, Pierre Génin, Laurent Meertens, Laura Sinigaglia, Nolwenn Jouvenet, Robert Weil, Nicoletta Casartelli, Caroline Demangel, Etienne Simon‐Lorière, Arnaud Moris, Philippe Roingeard, Ali Amara, and Olivier Schwartz
http://EMBOJ.embopress.org/content/36/12/1653?etoc

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Necroptosis and RIPKs
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Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
Gui-Wei He, Claudia Günther, Veronika Thonn, Yu-Qiang Yu, Eva Martini, Barbara Buchen, Markus F. Neurath, Michael Stürzl, and Christoph Becker
http://jem.rupress.org/content/214/6/1655?etoc

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury
Sofie Martens, Manhyung Jeong, Wulf Tonnus, Friederike Feldmann, Sam Hofmans, Vera Goossens, Nozomi Takahashi, Jan Hinrich Bräsen, Eun-Woo Lee, Pieter Van der Veken, Jurgen Joossens, Koen Augustyns, Simone Fulda, Andreas Linkermann, Jaewhan Song and Peter Vandenabeele
http://www.nature.com/cddis/journal/v8/n6/abs/cddis2017298a.html

Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis
Trieu-My Van, Apostolos Polykratis, Beate Katharina Straub, Vangelis Kondylis, Nikoletta Papadopoulou, Manolis Pasparakis
http://www.jci.org/articles/view/92508

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Death receptors
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Lymphadenopathy driven by TCR-Vγ8Vδ1 T-cell expansion in FAS-related autoimmune lymphoproliferative syndrome
Stefano Vavassori, Jacob D. Galson, Johannes Trück, Anke van den Berg, Rienk Y. J. Tamminga, Aude Magerus-Chatinet, Olivier Pellé, Ulrike Camenisch Gross, Ewerton Marques Maggio, Seraina Prader, Lennart Opitz, Ursina Nüesch, Andrea Mauracher, Benjamin Volkmer, Oliver Speer, Luzia Suda, Benno Röthlisberger, Dieter Robert Zimmermann, Rouven Müller, Arjan Diepstra, Lydia Visser, Eugenia Haralambieva, Bénédicte Neven, Frédéric Rieux-Laucat and Jana Pachlopnik Schmid
http://www.bloodadvances.org/content/1/15/1101

TNFR2 Stimulation Promotes Mitochondrial Fusion via Stat3- and NF-kB-Dependent Activation of OPA1 Expression
Jinliang Nan, Hengxun Hu, Yong Sun, Lianlian Zhu, Yingchao Wang, Zhiwei Zhong, Jing Zhao, Na Zhang, Ya Wang, Yaping Wang, Jian Ye, Ling Zhang, Xinyang Hu, Wei Zhu, Jian’an Wang
http://circres.ahajournals.org/content/early/2017/06/21/CIRCRESAHA.117.311143

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IAPs
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Selective replication of oncolytic virus M1 results in a bystander killing effect that is potentiated by Smac mimetics
Jing Cai, Yuan Lin, Haipeng Zhang, Jiankai Liang, Yaqian Tan, Webster K. Cavenee, and Guangmei Yan
http://www.pnas.org/content/114/26/6812.abstract.html?etoc

Ubiquitin-dependent regulation of Cdc42 by XIAP
Arun Murali, Jaeyoung Shin, Hajime Yurugi, Aswini Krishnan, Masato Akutsu, Alejandro Carpy, Boris Macek and Krishnaraj Rajalingam
http://www.nature.com/cddis/journal/v8/n6/abs/cddis2017305a.html

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Caspases
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Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development
Benjamin P. Weaver, Yi M. Weaver, Shohei Mitani, Min Han
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30395-7

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma
Giulia Fianco, Maria Patrizia Mongiardi, Andrea Levi, Teresa De Luca, Marianna Desideri, Daniela Trisciuoglio, Donatella Del Bufalo, Irene Cinà, Anna Di Benedetto, Marcella Mottolese, Antonietta Gentile, Diego Centonze, Fabrizio Ferrè and Daniela Barilà
https://elifesciences.org/articles/22593

Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma
H Janakiraman, R P House, S Talwar, S M Courtney, E S Hazard, G Hardiman, S Mehrotra, P H Howe, V Gangaraju and V Palanisamy
http://www.nature.com/onc/journal/v36/n22/abs/onc2016451a.html

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway
Xibao Liu , Baijuan Gong, Lorena Brito de Souza, Hwei Ling Ong, Krishna P. Subedi, Kwong Tai Cheng, William Swaim, Changyu Zheng, Yasuo Mori, Indu S. Ambudkar
http://stke.sciencemag.org/content/10/482/eaal4064

NLRC3 protein inhibits inflammation by disrupting NALP3 inflammasome assembly via competition with the adaptor protein ASC for pro-caspase-1 binding
Elif Eren, Mesut Berber, and Nesrin Özören
http://www.jbc.org/content/early/2017/06/05/jbc.M116.769695.abstract

RETRACTION: PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2
https://www.nature.com/onc/journal/v36/n25/full/onc20179a.html

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Bcl-2 family proteins
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Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1
Justin M Jenson, Jeremy A Ryan, Robert A Grant, Anthony Letai and Amy E Keating
https://elifesciences.org/articles/25541

Clinicopathological features and outcomes of progression of CLL on the BCL2 inhibitor venetoclax
Mary Ann Anderson, Constantine Tam, Thomas E. Lew, Surender Juneja, Manu Juneja, David Westerman, Meaghan Wall, Stephen Lade, Alexandra Gorelik, David C. S. Huang, John F. Seymour, and Andrew W. Roberts
http://www.bloodjournal.org/content/129/25/3362

Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia
M H A van Attekum, S Terpstra, E Slinger, M von Lindern, P D Moerland, A Jongejan, A P Kater and E Eldering
http://www.nature.com/onc/journal/v36/n26/abs/onc2016515a.html

A SYSTEMATIC REVIEW AND META-ANALYSIS OF INDIVIDUAL PATIENT DATA ON THE IMPACT OF THE BIM DELETION POLYMORPHISM ON TREATMENT OUTCOMES IN EPIDERMAL GROWTH FACTOR RECEPTOR MUTANT LUNG CANCER
Sheila X Soh, Fahad J Siddiqui, John C Allen, Go Woon Kim, Jae Cheol Lee, Yasushi Yatabe, Manabu Soda,Hiroyuki Mano, Ross A Soo, Tan-Min Chin, Hiromichi Ebi, Seiji Yano, Keitaro Matsuo, Xiaomin Niu, Shun Lu,Kazutoshi Isobe, Jih-Hsiang Lee, James C Yang, Mingchuan Zhao, Caicun Zhou, June-Koo Lee, Se-Hoon Lee, Ji Yun Lee, Myung-Ju Ahn, Tira J Tan, Daniel S Tan, Eng-Huat Tan, S. Tiong Ong, and Wan-Teck Lim
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=17102&path%5B%5D=54740

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Miscellaneous
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Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells
Lidia Bosurgi , Y. Grace Cao, Mar Cabeza-Cabrerizo, Andrea Tucci, Lindsey D. Hughes, Yong Kong, Jason S. Weinstein, Paula Licona-Limon, Edward T. Schmid, Facundo Pelorosso, Nicola Gagliani, Joseph E. Craft, Richard A. Flavell, Sourav Ghosh, Carla V. Rothlin
http://science.sciencemag.org/content/356/6342/1072

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth
Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, Julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton & Michele Pagano
http://www.nature.com/nature/journal/v546/n7659/full/nature22965.html

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
Angela Bononi, Carlotta Giorgi, Simone Patergnani, David Larson, Kaitlyn Verbruggen, Mika Tanji, Laura Pellegrini, Valentina Signorato, Federica Olivetto, Sandra Pastorino, Masaki Nasu, Andrea Napolitano, Giovanni Gaudino, Paul Morris, Greg Sakamoto, Laura K. Ferris, Alberto Danese, Andrea Raimondi, Carlo Tacchetti, Shafi Kuchay,Harvey I. Pass, El Bachir Affar, Haining Yang, Paolo Pinton & Michele Carbone
http://www.nature.com/nature/journal/v546/n7659/full/nature22798.html

IRE1α promotes viral infection by conferring resistance to apoptosis
Susan L. Fink , Teshika R. Jayewickreme, Ryan D. Molony, Takao Iwawaki, Charles S. Landis, Brett D. Lindenbach, Akiko Iwasaki
http://stke.sciencemag.org/content/10/482/eaai7814

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Reviews
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The Untold Story of Granzymes in Oncoimmunology: Novel Opportunities with Old Acquaintances
Maykel Arias, Luis Martínez-Lostao, Llipsy Santiago, Angel Ferrandez, David J. Granville, Julián Pardo
http://www.cell.com/trends/cancer/fulltext/S2405-8033(17)30067-5

BCL-2 family: integrating stress responses at the ER to control cell demise
Philippe Pihán, Amado Carreras-Sureda and Claudio Hetz
https://www.nature.com/cdd/journal/vaop/ncurrent/abs/cdd201782a.html

Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
Rama Rathore, Jennifer E. McCallum, Elizabeth Varghese, Ana-Maria Florea & Dietrich Büsselberg
https://link.springer.com/article/10.1007/s10495-017-1375-1

Necroptosis in neurodegenerative diseases: a potential therapeutic target
Shuo Zhang, Mi-bo Tang, Hai-yang Luo, Chang-he Shi and Yu-ming Xu
http://www.nature.com/cddis/journal/v8/n6/abs/cddis2017286a.html

Mitochondrial potassium channels in cell death
Vanessa Checchetto, Michele Azzolinib, Roberta Peruzzo,Paola Capitanio, Luigi Leanza
http://www.sciencedirect.com/science/article/pii/S0006291X17312263

Special issue on Ubiquitin in Inflammation and Cell Death: All roads lead to ubiquitin
Mads Gyrd-Hansen
http://www.nature.com/cdd/journal/v24/n7/full/cdd201793a.html

Including:
– Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling
Axel Witt and Domagoj Vucic
– CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different
Marie Lork, Kelly Verhelst and Rudi Beyaert
– Initiation and execution mechanisms of necroptosis: an overview
Sasker Grootjans, Tom Vanden Berghe and Peter Vandenabeele
– The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes
Rebecca Feltham and John Silke

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Comments – other
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SPATA2: more than a missing link
Lisa Schlicher, Prisca Brauns-Schubert, Florian Schubert and Ulrich Maurer
http://www.nature.com/cdd/journal/v24/n7/abs/cdd201726a.html

Partners in Crime
Barbara Conradt
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30458-6

DIE LATER WITH ESCRT!
Wulf Tonnus, Florian Gembardt, Christian Hugo, and Andreas Linkermann
http://dx.doi.org/10.18632/oncotarget.17903

Locked and loaded for apoptosis [cytochrome c]
Kara L. Bren , Emma L. Raven
http://science.sciencemag.org/content/356/6344/1236

BH3-only proteins: the thorny end of the ER stress response
Jason A Glab, Marcel Doerflinger and Hamsa Puthalakath
http://www.nature.com/cddis/journal/v8/n6/full/cddis2017283a.html

Cell scientist to watch – Mads Gyrd-Hansen
http://jcs.biologists.org/content/130/12/1981

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