Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for July, 2016

ApoList – June 2016

Posted by cris on July 10, 2016

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Necroptosis, RIPKs, death receptors
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RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D.
http://www.nature.com/cdd/journal/vaop/ncurrent/full/cdd201646a.html

Evolutionary divergence of the necroptosis effector MLKL
M C Tanzer, I Matti, J M Hildebrand, S N Young, A Wardak, A Tripaydonis, E J Petrie, A L Mildenhall, D L Vaux, J E Vince, P E Czabotar, J Silke and J M Murphy
http://www.nature.com/cdd/journal/v23/n7/abs/cdd2015169a.html

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
Jérémie Gautheron, Mihael Vucur, Anne T. Schneider, Ilenia Severi, Christoph Roderburg, Sanchari Roy, Matthias Bartneck, Peter Schrammen, Mauricio Berriel Diaz, Josef Ehling, Felix Gremse, Felix Heymann, Christiane Koppe, Twan Lammers, Fabian Kiessling, Niels Van Best, Oliver Pabst, Gilles Courtois, Andreas Linkermann, Stefan Krautwald,  Neumann UP9, Tacke F1, Trautwein C1,Green DR10, Longerich T11, Frey N12, Luedde M12, Bluher M13, Herzig S4,14, Heikenwalder M15, Luedde T1,2.
http://www.nature.com/ncomms/2016/160621/ncomms11869/full/ncomms11869.html

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH 3rd, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm 2, Verbist K, Gough PJ ,Bertin J, Hartmann BM, Sealfon SC, Kaiser WJ, Mocarski ES, López CB, Thomas PG, Oberst A, Green DR, Balachandran S
http://www.sciencedirect.com/science/article/pii/S1931312816302074

Engineered adenovirus fiber shaft fusion homotrimer of soluble TRAIL with enhanced stability and antitumor activity
J Yan, L Wang, Z Wang, Z Wang, B Wang, R Zhu, J Bi, J Wu, H Zhang, H Wu, B Yu, W Kong and X Yu
http://www.nature.com/cddis/journal/v7/n6/abs/cddis2016177a.html

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Engulfment and digestion
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Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response
Helen Weavers, Iwan R. Evans, Paul Martin, Will Wood
http://www.cell.com/cell/fulltext/S0092-8674(16)30494-9

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity
Vanja Sisirak, Benjamin Sally, Vivette D’Agati, Wilnelly Martinez-Ortiz, Z. Birsin Özçakar, Joseph David, Ali Rashidfarrokhi, Ada Yeste, Casandra Panea, Asiya Seema Chida, Milena Bogunovic, Ivaylo I. Ivanov, Francisco J. Quintana, Inaki Sanz, Keith B. E lkon, Mustafa Tekin, Fatoş Yalçınkaya, Timothy J. Cardozo, Robert M. Clancy, Jill P. Buyon, Boris Reizis
http://www.cell.com/cell/fulltext/S0092-8674(16)30585-2

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Caspases and IAPs
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Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF- α-dependent necroptosis driven by RIP1 kinase and NF-κB
M Oliver Metzig, D Fuchs, K E Tagscherer, H-J Gröne, P Schirmacher and W Roth
http://www.nature.com/onc/journal/v35/n26/full/onc2015398a.html

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
Ivan Zanoni , Yunhao Tan, Marco Di Gioia, Achille Broggi, Jianbin Ruan, Jianjin Shi, Carlos A. Donado, Feng Shao, Hao Wu, James R. Springstead, Jonathan C. Kagan
http://science.sciencemag.org/content/352/6290/1232

Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.
Zakaria Z, Tivnan A, Flanagan L, Murray DW, Salvucci M, Stringer BW, Day BW, Boyd AW, Kögel D, Rehm M, O’Brien DF, Byrne AT, Prehn JH.
http://www.nature.com/bjc/journal/v114/n2/full/bjc2015420a.html

Identification of caspase-6 as a new regulator of alternatively activated macrophages
Yongfang Yao, Qian Shi, Bing Chen, Qingsong Wang, Xinda Li, Long Li, Yahong Huang, Jianguo Ji, and Pingping Shen
http://www.jbc.org/content/early/2016/06/20/jbc.M116.717868.abstract

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Bcl-2 family proteins
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Pro-apoptotic Bax molecules densely populate the edges of membrane pores.
Kuwana T, Olson NH, Kiosses WB, Peters B, Newmeyer DD.
http://dx.doi.org/10.1038/srep27299

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak
Stephanie Einsele-Scholz, Silke Malmsheimer, Katrin Bertram, Daniel Stehle, Janina Johänning, Marianne Manz, Peter T. Daniel, Bernhard F. Gillissen, Klaus Schulze-Osthoff, and Frank Essmann
http://jcs.biologists.org/content/129/11/2213?etoc

Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis
E Raemy, S Montessuit, S Pierredon, A H van Kampen, F M Vaz and J-C Martinou
http://www.nature.com/cdd/journal/v23/n7/abs/cdd2015166a.html

MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria
Chong Teik Tan, Qi-Ling Zhou, Yu-Chin Su, Nai Yang Fu, Hao-Chun Chang, Ran N. Tao, Sunil K. Sukumaran, Shairaz Baksh, Yee-Joo Tan, Kanaga Sabapathy, Chun-Dong Yu, Victor C. Yu
http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30681-7

Bax/Bak activation in the absence of Bid, Bim, Puma, and p53
J Zhang, K Huang, K L O’Neill, X Pang and X Luo
http://www.nature.com/cddis/journal/v7/n6/abs/cddis2016167a.html

Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis
Flavie Strappazzon, Anthea Di Rita, Valentina Cianfanelli, Melania D’Orazio, Francesca Nazio, Gian Maria Fimia & Francesco Cecconi
http://www.tandfonline.com/doi/full/10.1080/15548627.2016.1164359#/doi/full/10.1080/15548627.2016.1164359

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex
Wataru Nakajima, Kanika Sharma, June Young Lee, Nicolas T. Maxim, Mark A. Hicks, Thien-Trang Vu, Angela Luu, W. Andrew Yeudall, Nobuyuki Tanaka,  and  Hisashi Harada
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=9217

miR-339-3p Is a Tumor Suppressor in Melanoma
[Mcl-1]
Claudia E.M. Weber, Chonglin Luo, Agnes Hotz-Wagenblatt, Adriane Gardyan,   Theresa Kordaß, Tim Holland-Letz, Wolfram Osen, and Stefan B. Eichmüller
http://cancerres.aacrjournals.org/content/76/12/3562.abstract?etoc

Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis
R Singh, S C Gupta, W-X Peng, N Zhou, R Pochampally, A Atfi, K Watabe, Z Lu and Y-Y Mo
http://www.nature.com/cddis/journal/v7/n6/abs/cddis2016168a.html

AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells.
Antonietti P, Gessler F, Düssmann H, Reimertz C, Mittelbronn M, Prehn JH, Kögel D.
http://www.sciencedirect.com/science/article/pii/S0167488915004371

The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism
Mary Ann Anderson, Jing Deng, John F. Seymour, Constantine Tam, Su Young Kim, Joshua Fein, Lijian Yu, Jennifer R. Brown, David Westerman, Eric G.  Si, Ian J. Majewski, David Segal, Sari L. Heitner Enschede, David C. S. Huang, Matthew S. Davids, Anthony Letai, and Andrew W. Roberts
http://bloodjournal.org/content/127/25/3215.abstract?etoc

BCR signaling inhibitors differ in their ability to overcome Mcl-1–mediated resistance of CLL B cells to ABT-199
Kamil Bojarczuk, Binu K. Sasi, Stefania Gobessi, Idanna Innocenti, Gabriele Pozzato, Luca Laurenti, and Dimitar G. Efremov
http://bloodjournal.org/content/127/25/3192.abstract?etoc

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Reviews
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An outline of necrosome triggers
Berghe, Tom Vanden; Hassannia, Behrouz; Vandenabeele, Peter
http://link.springer.com/article/10.1007%2Fs00018-016-2189-y

Targeting Cell Death Pathways for Therapeutic Intervention in Kidney Diseases
Jay P. Garg, Domagoj Vucic
http://www.seminarsinnephrology.org/article/S0270-9295(16)00023-1/abstract

Emerging roles for lipids in non-apoptotic cell death
L Magtanong, P J Ko and S J Dixon
http://www.nature.com/cdd/journal/v23/n7/abs/cdd201625a.html

Your neighbours matter – non-autonomous control of apoptosis in development and disease
M Eroglu and W B Derry
http://www.nature.com/cdd/journal/v23/n7/abs/cdd201641a.html

OPA1 processing in cell death and disease – the long and short of it
Thomas MacVicar and Thomas Langer
http://jcs.biologists.org/content/129/12/2297?etoc

Necroptosis and Inflammation
Kim Newton and Gerard Manning
http://www.annualreviews.org/doi/abs/10.1146/annurev-biochem-060815-014830

Caspases and their role in inflammation and ischemic neuronal death. Focus on caspase-12
Selene García de la Cadena & Lourdes Massieu
http://link.springer.com/article/10.1007/s10495-016-1247-0?wt_mc=alerts.TOCjournals

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Comments
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A BH3 Mimetic for Killing Cancer Cells
Douglas R. Green
http://www.cell.com/cell/fulltext/S0092-8674(16)30727-9

Cell Biology: ERADicating Survival with BOK
Jerry Edward Chipuk, Mark P. Luna-Vargas
http://mail.elsevierhealth.com/cgi-bin23/DM/x/nBCAu0KmluD0Rf80BZ2D50EA

To BH3 profile or not to BH3 profile
Matthew D. Blunt and Andrew J. Steele
http://bloodjournal.org/content/127/25/3111?etoc

Bok modulates apoptosis sensitivity
http://jcs.biologists.org/content/129/11/e1104?etoc

Primed for inflammation by past meals
Wei Wong
http://stke.sciencemag.org/content/9/434/ec149

Redefining the roles of apoptotic factors in carcinogenesis
Xinjian Liu, Yujun He, Fang Li, Qian Huang, Takamitsu A. Kato, Russell P. Hall & Chuan-Yuan Li
http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1054550

A mitosis-sensing caspase activation platform? New insights into the PIDDosome
Richa B. Shah, Ruth Thompson & Samuel Sidi
http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1059921

USP11: A key regulator of cIAP2 stability and sensitivity to SMAC mimetics
Eun-Woo Lee & Jaewhan Song
http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1029829

Dynamic BH3 profiling-poking cancer cells with a stick
Joan Montero & Anthony Letai
http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1040144

Ferroptosis: A missing puzzle piece in the p53 blueprint?
Shang-Jui Wang, Yang Ou, Le Jiang & Wei Gu
http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1046581

Raptor hunted by caspases
R Martin, M Thome, F Martinon and N Fasel
http://www.nature.com/cddis/journal/v7/n6/full/cddis2016153a.html

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Retractions
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Sirtuin-3 deacetylation of cyclophilin D induces dissociation of
hexokinase II from the mitochondria
Nataly Shulga, Robin Wilson-Smith, and John G. Pastorino

Ethanol sensitizes mitochondria to the permeability transition by
inhibiting deacetylation of cyclophilin-D mediated by sirtuin-3
Nataly Shulga and John G. Pastorino

GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for
TNF-induced necroptosis
Nataly Shulga and John G. Pastorino

Sirtuin-3 modulates Bak- and Bax-dependent apoptosis
Manish Verma, Nataly Shulga, and John G. Pastorino

Mitoneet mediates TNFα-induced necroptosis promoted by exposure to
fructose and ethanol
Nataly Shulga and John G. Pastorino

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