Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for February, 2015

ApoList – January 2015

Posted by cris on February 1, 2015

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Bcl-2 family proteins
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Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis
Thibaud T. Renault, Konstantinos V. Floros, Rana Elkholi, Kelly-Ann Corrigan, Yulia Kushnareva, Shira Y. Wieder, Claudia Lindtner, Madhavika N. Serasinghe, James J. Asciolla, Christoph Buettner, Donald D. Newmeyer, Jerry E. Chipuk
http://www.cell.com/molecular-cell/abstract/S1097-2765(14)00863-6

Differential retrotranslocation of mitochondrial Bax and Bak
Franziska Todt, Zeynep Cakir, Frank Reichenbach, Frederic Emschermann, Joachim Lauterwasser, Andrea Kaiser, Gabriel Ichim, Stephen WG Tait, Stephan Frank, Harald F Langer, and Frank Edlich
http://EMBOJ.embopress.org/content/34/1/67?etoc

Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes
Laura A Gillies, Han Du, Bjoern Peters, C. Michael Knudson, Donald D. Newmeyer, and Tomomi Kuwana
http://www.molbiolcell.org/content/26/2/339.abstract?etoc

The BH3-only protein Bad is dispensable for TNF-mediated cell death
E Ottina, M Sochalska, R Sgonc and A Villunger
http://www.nature.com/cddis/journal/v6/n1/abs/cddis2014575a.html

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells
Duohui Jing, Vivek A. Bhadri, Dominik Beck, Julie A. I. Thoms, Nurul A. Yakob, Jason W. H. Wong, Kathy Knezevic, John E. Pimanda, and Richard B. Lock
http://bloodjournal.org/content/125/2/273.abstract?etoc

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim dependent fashion
Elena Catalán, Paula Jaime-Sánchez, Nacho Aguiló, Markus M. Simon, Christopher J. Froelich, and Julián Pardo
http://www.jbc.org/content/early/2015/01/20/jbc.M114.631564.abstract

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma
Cristina Correia, Paula A. Schneider, Haiming Dai, Ahmet Dogan, Matthew J. Maurer, Amy K. Church, Anne J. Novak, Andrew L. Feldman, Xiaosheng Wu,Husheng Ding, X. Wei Meng, James R. Cerhan, Susan L. Slager, William R. Macon, Thomas M. Habermann, Judith E. Karp, Steven D. Gore, Neil E. Kay, Diane F. Jelinek, Thomas E. Witzig, Grzegorz S. Nowakowski, and Scott H. Kaufmann
http://bloodjournal.org/content/125/4/658.abstract?etoc

Characterisation of a novel A1-specific monoclonal antibody
M J Lang, M S Brennan, L A O’Reilly, E Ottina, P E Czabotar, E Whitlock, W D Fairlie, L Tai, A Strasser and M J Herold
http://www.nature.com/cddis/journal/v5/n12/full/cddis2014519a.html?WT.ec_id=CDDIS-201412

MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies
G S Choudhary, S Al-harbi, S Mazumder, B T Hill, M R Smith, J Bodo, E D Hsi and A Almasan
http://www.nature.com/cddis/journal/v6/n1/abs/cddis2014525a.html

DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX
J-J Guan, X-D Zhang, W Sun, L Qi, J-C Wu and Z-H Qin
http://www.nature.com/cddis/journal/v6/n1/abs/cddis2014546a.html

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
J D Leverson, H Zhang, J Chen, S K Tahir, D C Phillips, J Xue, P Nimmer, S Jin, M Smith, Y Xiao, P Kovar, A Tanaka, M Bruncko, G S Sheppard, L Wang, S Gierke, L Kategaya, D J Anderson, C Wong, J Eastham-Anderson, M J C Ludlam, D Sampath, W J Fairbrother, I Wertz, S H Rosenberg, C Tse, S W Elmore and A J Souers
http://www.nature.com/cddis/journal/v6/n1/abs/cddis2014561a.html

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Death receptors and FADD
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Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL
T Sánchez-Pérez, R H Medema and A López-Rivas
http://www.nature.com/onc/journal/v34/n5/abs/onc2013601a.html

Genome-Wide Identification of Fas/CD95 Alternative Splicing Regulators Reveals Links with Iron Homeostasis
J. Ramón Tejedor, Panagiotis Papasaikas, Juan Valcárcel
http://www.cell.com/molecular-cell/abstract/S1097-2765(14)00864-8

Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer
Brittany M. Bowman, Katrina A. Sebolt, Benjamin A. Hoff, Jennifer L. Boes, Danette L. Daniels, Kevin A. Heist, Craig J. Galbán, Rajiv M. Patel, Jianke Zhang, David G. Beer, Brian D. Ross, Alnawaz Rehemtulla, and Stefanie Galbán
http://stke.sciencemag.org/content/8/361/ra9.abstract

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Non-apoptotic cell death/caspase-8
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Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
S Saveljeva, S L Mc Laughlin, P Vandenabeele, A Samali and M J M Bertrand
http://www.nature.com/cddis/journal/v6/n1/full/cddis2014548a.html

RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions
Y Estornes, M A Aguileta, C Dubuisson, J De Keyser, V Goossens, K Kersse, A Samali, P Vandenabeele and M J M Bertrand
http://www.nature.com/cddis/journal/v5/n12/abs/cddis2014523a.html?WT.ec_id=CDDIS-201412

RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells
Guozhu Chen , Xiang Cheng , Ming Zhao , Song Lin , Jiangyang Lu , Jiarui Kang & Xiaodan Yu
http://link.springer.com/article/10.1007/s10495-014-1058-0?wt_mc=alerts.TOCjournals

A RIPK3–Caspase 8 Complex Mediates Atypical Pro–IL-1β Processing
Kenta Moriwaki, John Bertin, Peter J. Gough and Francis Ka-Ming Chan
http://www.jimmunol.org/content/early/2015/01/06/jimmunol.1402167.abstract

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Caspases and IAPs
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Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment.
Varfolomeev E, Izrael-Tomasevic A, Yu K, Bustos D, Goncharov T, Belmont LD, Masselot A, Bakalarski CE, Kirkpatrick DS, Vucic D.
http://www.biochemj.org/bj/imps/abs/BJ20141195.htm

Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response
I Eckhardt, A Weigert and S Fulda
http://www.nature.com/cddis/journal/v5/n12/abs/cddis2014498a.html

XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis
M Ehrenschwender, S Bittner, K Seibold and H Wajant
http://www.nature.com/cddis/journal/v5/n12/abs/cddis2014534a.html

Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
E Kavanagh, J Rodhe, M A Burguillos, J L Venero and B Joseph
http://www.nature.com/cddis/journal/v5/n12/abs/cddis2014514a.html

Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice
C H Wilson, S Shalini, A Filipovska, T R Richman, S Davies, S D Martin, S L McGee, J Puccini, A Nikolic, L Dorstyn and S Kumar
http://www.nature.com/cddis/journal/v6/n1/abs/cddis2014567a.html

Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate
A Aries, J Whitcomb, W Shao, H Komati, M Saleh and M Nemer
http://www.nature.com/cddis/journal/v5/n12/abs/cddis2014524a.html

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Phagocytosis and other consequences
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Apico-basal forces exerted by apoptotic cells drive epithelium folding
Bruno Monier, Melanie Gettings, Guillaume Gay, Thomas Mangeat, Sonia Schott, Ana Guarner & Magali Suzanne
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14152.html

A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells
Hengwen Yang, Yu-Zen Chen, Yi Zhang, Xiaohui Wang, Xiang Zhao, James I. Godfroy, Qian Liang, Man Zhang, Tianying Zhang, Quan Yuan, Mary Ann Royal, Monica Driscoll, Ning-Shao Xia, Hang Yin and Ding Xue
http://www.nature.com/ncomms/2015/150107/ncomms6717/full/ncomms6717.html

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Miscellaneous
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Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity
Martina Haller, Andreas K Hock, Evangelos Giampazolias, Andrew Oberst, Douglas R Green, Jayanta Debnath, Kevin M Ryan, Karen H Vousden & Stephen W G Tait
http://www.tandfonline.com/doi/abs/10.4161/15548627.2014.981914?ai=1gmor&ui=79l0u&af=T

GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis
Michael Wrzaczek, Julia P Vainonen, Simon Stael, Liana Tsiatsiani, Hanna Help‐Rinta‐Rahko, Adrien Gauthier, David Kaufholdt, Benjamin Bollhöner, Airi Lamminmäki, An Staes, Kris Gevaert, Hannele Tuominen, Frank Van Breusegem, Ykä Helariutta, and Jaakko Kangasjärvi
http://EMBOJ.embopress.org/content/34/1/55?etoc

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway
Brent Neumann, Sean Coakley, Rosina Giordano-Santini, Casey Linton, Eui Seung Lee, Akihisa Nakagawa, Ding Xue & Massimo A. Hilliard
http://www.nature.com/nature/journal/v517/n7533/full/nature14102.html

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Reviews
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Necroptosis and its role in inflammation
Manolis Pasparakis, Peter Vandenabeele
http://www.nature.com/nature/journal/v517/n7534/full/nature14191.html

Programmed necrosis and necroptosis signalling
Maria Feoktistova and Martin Leverkus
http://onlinelibrary.wiley.com/enhanced/doi/10.1111/febs.13120/

RIP kinases: key decision makers in cell death and innate immunity
F Humphries, S Yang, B Wang and P N Moynagh
http://www.nature.com/cdd/journal/v22/n2/abs/cdd2014126a.html

Die for the community: an overview of programmed cell death in bacteria
N Allocati, M Masulli, C Di Ilio and V De Laurenzi
http://www.nature.com/cddis/journal/v6/n1/full/cddis2014570a.html

Autophagy as a pro-death pathway
Donna Denton, Tianqi Xu and Sharad Kumar
http://www.nature.com/icb/journal/v93/n1/full/icb201485a.html

TMBIM protein family: ancestral regulators of cell death
D Rojas-Rivera and C Hetz
http://www.nature.com/onc/journal/v34/n3/full/onc20146a.html

The domains of apoptosis and inflammation
Hyun Ho Park
http://link.springer.com/article/10.1007/s10495-014-1050-8?wt_mc=alerts.TOCjournals

Tandem DEDs and CARDs suggest novel mechanisms of signaling complex assembly
Yu-Chih Lo , Su-Chang Lin , Chao-Yu Yang & Jung-Yu Tung
http://link.springer.com/article/10.1007/s10495-014-1054-4?wt_mc=alerts.TOCjournals

The Bcl-2 family: structures, interactions and targets for drug discovery
Marc Kvansakul & Mark G. Hinds
http://link.springer.com/article/10.1007/s10495-014-1051-7?wt_mc=alerts.TOCjournals

The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling
Wen-Pin Kao , Chao-Yu Yang , Tsung-Wei Su , Yin-Ting Wang , Yu-Chih Lo & Su-Chang Lin
http://link.springer.com/article/10.1007/s10495-014-1062-4?wt_mc=alerts.TOCjournals

Structural basis of cell apoptosis and necrosis in TNFR signaling
Jing Huang , Shaoning Yu , Chaoneng Ji & Jixi Li
http://link.springer.com/article/10.1007/s10495-014-1061-5?wt_mc=alerts.TOCjournals

Hijacking of death receptor signaling by bacterial pathogen effectors
Jie Luo , Jiaqingzi Hu , Yong Zhang , Qing Hu & Shan Li
http://link.springer.com/article/10.1007/s10495-014-1068-y?wt_mc=alerts.TOCjournals

Death effecter domain for the assembly of death-inducing signaling complex
Jin Kuk Yang
http://link.springer.com/article/10.1007/s10495-014-1060-6?wt_mc=alerts.TOCjournals

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Methods, comments, other
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Imaging-based methods for assessing caspase activity in single cells.
Parsons MJ, Rehm M, Bouchier-Hayes L.
http://cshprotocols.cshlp.org/content/2015/1/pdb.top070342.abstract

Measuring caspase activity by förster resonance energy transfer.
Rehm M, Parsons MJ, Bouchier-Hayes L.
http://cshprotocols.cshlp.org/content/2015/1/pdb.prot082560.abstract

Measuring initiator caspase activation by bimolecular fluorescence complementation.
Parsons MJ, Bouchier-Hayes L.
http://cshprotocols.cshlp.org/content/2015/1/pdb.prot082552.abstract

Cell biology: Death drags down the neighbourhood
Claudia G. Vasquez & Adam C. Martin
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14198.html

Stefan Grimm, 1963–2014, a tragic loss for the scientific community
A-L Mahul-Mellier, L Huc, A Lemarié, S Irshad, M Hwang, C Datler and E Pazarentzos
http://www.nature.com/cdd/journal/v22/n2/full/cdd2014196a.html

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