Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for July, 2013

ApoList – July 2013

Posted by cris on July 31, 2013

——————————–
Bcl-2 family proteins
——————————–

Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK
A Geissler, F Haun, D O Frank, K Wieland, M M Simon, M Idzko, R J Davis, U Maurer and C Borner
http://www.nature.com/cdd/journal/vaop/ncurrent/full/cdd201378a.html

The p53–PUMA axis suppresses iPSC generation
Yanxin Li, Haizhong Feng, Haihui Gu, Dale W. Lewis, Youzhong Yuan, Lei Zhang, Hui Yu, Peng Zhang, Haizi Cheng, Weimin Miao, Weiping Yuan, Shi-Yuan Cheng, Susanne M. Gollin and Tao Cheng
http://www.nature.com/ncomms/2013/130722/ncomms3174/full/ncomms3174.html

Zinc-induced modulation of SRSF6 activity alters Bim splicing to promote generation of the most potent apoptotic isoform BimS
Hirokazu Hara, Tatsuya Takeda, Nozomi Yamamoto, Keisuke Furuya, Kazuya Hirose, Tetsuro Kamiya and Tetsuo Adachi
http://onlinelibrary.wiley.com/doi/10.1111/febs.12318/abstract

A pre-miR-149 genetic variation affects miR-149 maturation and its ability to regulate Puma in apoptosis
Su-Ling Ding, Jian-Xun Wang, Jian-Qin Jiao, Xin Tu, Qing Wang, Fang Liu, Qian Li, Jie Gao, Qun-Yong Zhou, Dong-Feng Gu, and Pei-Feng Li
http://www.jbc.org/cgi/content/abstract/M112.440453v1?papetoc

Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer
François Vaillant, Delphine Merino, Lily Lee, Kelsey Breslin, Bhupinder Pal, Matthew E. Ritchie, Gordon K. Smyth, Michael Christie, Louisa J. Phillipson, Christopher J. Burns, G. Bruce Mann, Jane E. Visvader, Geoffrey J. Lindeman
http://www.cell.com/cancer-cell/abstract/S1535-6108(13)00278-X

Mcl-1 antagonizes Bax/Bak to promote effector CD4+ and CD8+ T-cell responses
P Tripathi, B Koss, J T Opferman and D A Hildeman
http://www.nature.com/cdd/journal/v20/n8/abs/cdd201325a.html

A Bcl-xL–Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis
Hongmei Li, Kambiz N. Alavian, Emma Lazrove, Nabil Mehta, Adrienne Jones, Ping Zhang, Pawel Licznerski, Morven Graham, Takuma Uo, Junhua Guo, Christoph Rahner, Ronald S. Duman, Richard S. Morrison & Elizabeth A. Jonas
http://www.nature.com/ncb/journal/v15/n7/full/ncb2791.html

The BCL-2 family member bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage
Jacqualyn J. Schulman, Forrest A. Wright, Thomas Kaufmann, and Richard J.
H. Wojcikiewicz
http://www.jbc.org/cgi/content/abstract/M113.496570v1?papetoc

————————————-
Death receptor pathway
————————————-

RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex
B A Abhari, S Cristofanon, R Kappler, D von Schweinitz, R Humphreys and S Fulda
http://www.nature.com/onc/journal/v32/n27/abs/onc2012337a.html

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways
M van Dijk, A Halpin-McCormick, T Sessler, A Samali and E Szegezdi
http://www.nature.com/cddis/journal/v4/n7/abs/cddis2013214a.html

Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Shidrokh Ardestani, Bin Li, Desirae L. Deskins, Huiyun Wu, Pierre P. Massion, and Pampee P. Young
http://cancerres.aacrjournals.org/content/73/13/3938.abstract.html

Targeting Transmembrane TNF-α Suppresses Breast Cancer Growth
Mingxia Yu, Xiaoxi Zhou, Lin Niu, Guohong Lin, Jin Huang, Wenjing Zhou, Hui Gan, Jing Wang, Xiaodan Jiang, Bingjiao Yin, and Zhuoya Li
http://cancerres.aacrjournals.org/content/73/13/4061.abstract.html

TRAIL-induced miR-146a expression suppresses CXCR4-mediated human breast cancer migration
Dongsheng Wang, Dan Liu, Jing Gao, Min Liu, Shilian Liu, Minghong Jiang, Yanxin Liu and Dexian Zheng
http://onlinelibrary.wiley.com/doi/10.1111/febs.12323/abstract

Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes
Vladimira Horova, Nada Hradilova, Iva Jelinkova, Michal Koc, Jan Svadlenka, Jan Brazina, Martin Klima, Josef Slavik, Alena Hyrslova Vaculova and Ladislav Andera
http://onlinelibrary.wiley.com/doi/10.1111/febs.12347/abstract

Lymphotoxin  induces apoptosis, necroptosis and inflammatory signals with the same potency as TNF
Nima Etemadi, Jessica K. Holien, Diep Chau, Grant Dewson, James M. Murphy, Warren S. Alexander, Michael W. Parker, John Silke and Ueli Nachbur
http://onlinelibrary.wiley.com/doi/10.1111/febs.12419/abstract

Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes
Deborah A. Flusberg, Jérémie Roux, Sabrina L. Spencer, and Peter K. Sorger
http://www.molbiolcell.org/content/24/14/2186.abstract?etoc

—————————————————————————–
Caspases and downstream / metacaspases / IAPs
—————————————————————————–

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
Jun Suzuki, Daniel P. Denning, Eiichi Imanishi, H. Robert Horvitz, Shigekazu Nagata
http://www.sciencemag.org/content/341/6144/403.abstract

Determining the contributions of caspase-2, caspase-8 and effector caspases to intracellular VDVADase activities during apoptosis initiation and execution
M. Eugenia Delgado, Magnus Olsson, Frank A. Lincoln, Boris Zhivotovsky, Markus Rehm
http://www.sciencedirect.com/science/article/pii/S0167488913002152

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
Damgaard RB, Fiil BK, Speckmann C, Yabal M, Stadt UZ, Bekker-Jensen S, Jost PJ, Ehl S, Mailand N, Gyrd-Hansen M.
http://onlinelibrary.wiley.com/doi/10.1002/emmm.201303090/abstract

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.
Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, Roberts TL, Schroder K, Vince JE, Hill JM, Silke J, Stacey KJ.
http://www.nature.com/cdd/journal/vaop/ncurrent/full/cdd201337a.html

Caspase-2 Short Isoform Interacts with Membrane-Associated Cytoskeleton Proteins to Inhibit Apoptosis
Chunhua Han, Ran Zhao, John Kroger, Meihua Qu, Altaf A. Wani, Qi-En Wang
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067033

Biochemical evidence of key residues for the activation and autoprocessing of tomato type II metacaspase
Shuai Wen, Qiu-Min Ma, Ya-Li Zhang, Ji-Ping Yang, Guang-Hua Zhao, Da-Qi Fu, Yun-Bo Luo, Gui-Qin Qu
http://www.sciencedirect.com/science/article/pii/S0014579313005231

Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage
Jiao Zhang, Xin Wang, Wenjing Cui, Wenwen Wang, Huamei Zhang, Lu Liu, Zicheng Zhang, Zheng Li, Guoguang Ying, Ning Zhang and Binghui Li
http://www.nature.com/ncomms/2013/130716/ncomms3157/full/ncomms3157.html

Caspase Activity Is Required for Engulfment of Apoptotic Cells
Boris Shklyar, Flonia Levy-Adam, Ketty Mishnaevski, and Estee Kurant
http://mcb.asm.org/cgi/content/abstract/33/16/3191?etoc

————————————-
Non apoptotic cell death
————————————-

GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death
M A Jacquin, J Chiche, B Zunino, M Bénéteau, O Meynet, L A Pradelli, S Marchetti, A Cornille, M Carles and J-E Ricci
http://www.nature.com/cdd/journal/v20/n8/abs/cdd201332a.html

Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
Andreas Linkermann, Jan Hinrich Bräsen, Maurice Darding, Mi Kyung Jin, Ana B. Sanz, Jan-Ole Heller, Federica De Zen, Ricardo Weinlich, Alberto Ortiz, Henning Walczak, Joel M. Weinberg, Douglas R. Green, Ulrich Kunzendorf, and Stefan Krautwald
http://www.pnas.org/content/110/29/12024.abstract.html?etoc

Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia
S J Kim and Jianrong Li
http://www.nature.com/cddis/journal/v4/n7/abs/cddis2013238a.html

———————–
Miscellaneous
———————–

An Sp1 transcription factor coordinates caspase-dependent and -independent apoptotic pathways
Takashi Hirose, H. Robert Horvitz
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12329.html

Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c
Reiko Ban-Ishihara, Takaya Ishihara, Narie Sasaki, Katsuyoshi Mihara, and Naotada Ishihara
http://www.pnas.org/content/110/29/11863.abstract.html?etoc

——————
Reviews
——————

Paracrine control of tissue regeneration and cell proliferation by Caspase-3
K Boland, L Flanagan and J HM Prehn
http://www.nature.com/cddis/journal/v4/n7/abs/cddis2013250a.html

Rejuvenating Bi(d)ology
S S Zinkel, X M Yin and A Gross
http://www.nature.com/onc/journal/v32/n27/abs/onc2012454a.html

Anoikis molecular pathways and its role in cancer progression
Paolo Paoli, Elisa Giannoni, Paola Chiarugi
http://www.sciencedirect.com/science/article/pii/S0167488913002498

ER stress-induced cell death mechanisms
Renata Sano, John C. Reed
http://www.sciencedirect.com/science/article/pii/S0167488913002516

——————————–
Previews / comments
——————————–

Another twist in the on and off affair between cell suicide and inflammation
D L Vaux
http://www.nature.com/cdd/journal/v20/n8/full/cdd201357a.html

Antiinflammatory effects of apoptotic cells
Peter M. Henson, Donna L. Bratton
http://www.jci.org/articles/view/69344

Guarding effector T-cell survival: all for one, Mcl-1 for all?
E Ottina, M Pellegrini and A Villunger
http://www.nature.com/cdd/journal/v20/n8/full/cdd201355a.html

BCL-2: A New Therapeutic Target in Estrogen Receptor-Positive Breast Cancer?
Lesley-Ann Martin, Mitch Dowsett
http://www.cell.com/cancer-cell/abstract/S1535-6108(13)00282-1

XiAP-ping Castration-Resistant Prostate Cancer
The XAF1-XIAP pathway provides a mechanistic link and a path for personalized prostate cancer therapy.
http://stm.sciencemag.org/content/5/192/192ec111.short

Whence the “Eat Me” Signal?
An enzyme involved in the flipping of phospholipids in dying cells’ surfaces to mark the cells for removal is identified.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/286/ec180

————
Other
————

Cold Spring Harbor Laboratory Cell Death Meeting Oct 8-12 2013: Abstract Deadline Extended to August 11
http://meetings.cshl.edu/meetings/2013/pcd13.shtml

——————————————————-
——————————————————-
——————————————————-

Advertisements

Posted in Uncategorized | Leave a Comment »

ApoList – June 2013

Posted by cris on July 1, 2013

 

——————————-
Bcl-2 family proteins
——————————-

Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction
Xi Wang, Madhavi Bathina, John Lynch, Brian Koss, Christopher Calabrese, Sharon Frase, John D. Schuetz, Jerold E. Rehg, and Joseph T. Opferman
http://genesdev.cshlp.org/content/27/12/1351.abstract.html

Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure
Robert L. Thomas, David J. Roberts, Dieter A. Kubli, Youngil Lee, Melissa N. Quinsay, Jarvis B. Owens, Kimberlee M. Fischer, Mark A. Sussman, Shigeki Miyamoto, and Åsa B. Gustafsson
http://genesdev.cshlp.org/content/27/12/1365.abstract.html

The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm−/− mice
S Biswas, Q Shi, A Wernick, A Aiello and S S Zinkel
http://www.nature.com/cdd/journal/v20/n7/abs/cdd201316a.html

tBid undergoes multiple conformational changes at the membrane required for Bax activation
Aisha Shamas-Din, Scott Bindner, Weijia Zhu, Yehudit Zaltsman, Clinton Campbell, Atan Gross, Brian Leber, David W. Andrews, and Cécile Fradin
http://www.jbc.org/cgi/content/abstract/M113.482109v2

Control of Cellular Bcl-xL Levels by Deamidation-Regulated Degradation
So Hee Dho, Benjamin E. Deverman, Carlo Lapid, Scott R. Manson, Lu Gan, Jacob J. Riehm, Rajeev Aurora, Ki-Sun Kwon, Steven J. Weintraub
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001588

MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R
J Gong, J-P Zhang, B Li, C Zeng, K You, M-X Chen, Y Yuan and S-M Zhuang
http://www.nature.com/onc/journal/v32/n25/abs/onc2012318a.html

BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR
Clémentine Aguirre, Tim ten Brink, Olivier Walker, Florence Guillière, Dany Davesne, Isabelle Krimm
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064400

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts
Diana M. González-Gironès, Cristina Moncunill-Massaguer, Daniel Iglesias-Serret, Ana M. Cosialls, Alba Pérez-Perarnau, Claudia M. Palmeri, Camila Rubio-Patiño, Andreas Villunger, Gabriel Pons & Joan Gil
http://link.springer.com/article/10.1007/s10495-013-0850-6

Consequences of the combined loss of BOK and BAK or BOK and BAX
F Ke, P Bouillet, T Kaufmann, A Strasser, J Kerr and A K Voss
http://www.nature.com/cddis/journal/v4/n6/abs/cddis2013176a.html

Three-dimensional structure of Bax-mediated pores in membrane bilayers
X-P Xu, D Zhai, E Kim, M Swift, J C Reed, N Volkmann and D Hanein
http://www.nature.com/cddis/journal/v4/n6/abs/cddis2013210a.html

————————
Death receptors
————————

Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors
T Bagci-Onder, A Agarwal, D Flusberg, S Wanningen, P Sorger and K Shah
http://www.nature.com/onc/journal/v32/n23/abs/onc2012304a.html

Structural And Biophysical Characterization Of The Interactions Between The Death Domain Of Fas Receptor And Calmodulin
Timothy F. Fernandez, Alexandra B. Samal, Gregory J. Bedwell, Yabing Chen, and Jamil S. Saad
http://www.jbc.org/cgi/content/abstract/M113.471821v1

Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex
Jillian F. Wise, Zuzana Berkova, Rohit Mathur, Haifeng Zhu, Frank K. Braun, Rong-Hua Tao, Anita L. Sabichi, Xue Ao, Hoyoung Maeng, and Felipe Samaniego
http://bloodjournal.hematologylibrary.org/content/121/23/4729.abstract.html

—————-
Caspases
—————-

Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles
A.N. Böing, J. Stap, C.M. Hau, G.B. Afink, C. Ris-Stalpers, E.A. Reits, A. Sturk, C.J.F. van Noorden, R. Nieuwland
http://www.sciencedirect.com/science/article/pii/S0167488913001146

Inhibition of hepatocyte autophagy increases tumor necrosis factor-dependent liver injury by promoting caspase-8 activation
M Amir, E Zhao, L Fontana, H Rosenberg, K Tanaka, G Gao and M J Czaja
http://www.nature.com/cdd/journal/v20/n7/abs/cdd201321a.html

Bioluminescence imaging of caspase-3 activity in mouse liver
Qiuxia Fu, Xiangguo Duan, Shaoduo Yan, Licui Wang, Yong Zhou, Shuaizheng Jia, Juan Du, Xiaohui Wang, Yuhua Zhang & Linsheng Zhan
http://link.springer.com/article/10.1007/s10495-013-0849-z

———————
Miscellaneous
———————

Cell death proteomics database: consolidating proteomics data on cell death.
Arntzen MØ, Bull VH, Thiede B.
http://dx.doi.org/10.1021/pr4000703
http://celldeathproteomics.uio.no

The Indirect Activation Model of Mitochondrial Outer Membrane Permeabilisation (MOMP) Initiation requires a Trade-off between Robustness in Absence, and Sensitivity in Presence of Stress
Andreas U Lindner,   Jochen HM Prehn and   Heinrich J Huber
http://pubs.rsc.org/en/content/articlelanding/2013/mb/c3mb70076c/unauth

Rotenone induces neuronal death by microglial phagocytosis of neurons
Julius V. Emmrich, Tamara C. Hornik, Jonas J. Neher and Guy C. Brown
http://onlinelibrary.wiley.com/doi/10.1111/febs.12401/abstract

————-
Reviews
————-

Developmentally Programmed Cell Death in Drosophila
Donna Denton, May T. Aung-Htut, Sharad Kumar
http://www.sciencedirect.com/science/article/pii/S0167488913002371

Decoding and unlocking the BCL-2 dependency of cancer cells
Philippe Juin, Olivier Geneste, Fabien Gautier, Stéphane Depil & Mario Campone
http://www.nature.com/nrc/journal/v13/n7/abs/nrc3538.html

Central roles of apoptotic proteins in mitochondrial function
S M Kilbride and J H M Prehn
http://www.nature.com/onc/journal/v32/n22/abs/onc2012348a.html

Mature neurons: equipped for survival
A J Kole, R P Annis and M Deshmukh
http://www.nature.com/cddis/journal/v4/n6/abs/cddis2013220a.html

Immunogenic tumor cell death induced by chemoradiotherapy: molecular mechanisms and a clinical translation
K Kono, K Mimura and R Kiessling
http://www.nature.com/cddis/journal/v4/n6/abs/cddis2013207a.html

Crosstalk between apoptosis, necrosis and autophagy
Vassiliki Nikoletopoulou, Maria Markaki, Konstantinos Palikaras, Nektarios Tavernarakis
http://www.sciencedirect.com/science/article/pii/S0167488913002243

Cell death by cornification
Leopold Eckhart, Saskia Lippens, Erwin Tschachler, Wim Declercq
http://www.sciencedirect.com/science/article/pii/S0167488913002334

Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
K Azijli, B Weyhenmeyer, G J Peters, S de Jong and F A E Kruyt
http://www.nature.com/cdd/journal/v20/n7/abs/cdd201328a.html

————————
Previews / other
————————

Bid-ding for mercy: twisted killer in action
A Egle, D Asslaber, A Villunger and J Pinon-Hofbauer
http://www.nature.com/cdd/journal/v20/n7/full/cdd201340a.html

The dark side of TRAIL signaling
S Fulda
http://www.nature.com/cdd/journal/v20/n7/full/cdd201336a.html

Adaptation to Starvation: Translating a Matter of Life or Death
Brendan D. Manning
http://www.cell.com/cancer-cell/abstract/S1535-6108(13)00237-7

Extracellular Adenosine Induces p53-Dependent Cell Death
http://cancerdiscovery.aacrjournals.org/content/3/6/OF9.abstrac.html

Cell death: A2B via p53
http://www.nature.com/nrc/journal/v13/n7/full/nrc3548.html

What Makes You Can Also Break You, Part II: Mitochondrial Permeability Transition Pore Formation by Dimers of the F1FO ATP-Synthase?
Gyorgy Szabadkai and Christos Chinopoulos
http://www.frontiersin.org/molecular_and_cellular_oncology/10.3389/fonc.2013.00140/full

Vital dyes and virtual deaths
M Husmann
http://www.nature.com/cdd/journal/v20/n7/full/cdd201327a.html


Apoptosis Methods
Edited by Seamus J. Martin and Conor M. Henry
http://www.sciencedirect.com/science/journal/10462023/61/2
http://www.sciencedirect.com/science/article/pii/S104620231300193X

Including:

– Measuring apoptosis by microscopy and flow cytometry
Conor M. Henry, Emilie Hollville, Seamus J. Martin
– Isolation, characterisation and reconstitution of cell death signalling complexes
Michelle A. Hughes, Claudia Langlais, Kelvin Cain, Marion MacFarlane
– In vivo assessment of specific cytotoxic T lymphocyte killing
T. Clemente, M.R. Dominguez, N.J. Vieira, M.M. Rodrigues, G.P. Amarante-Mendes
– Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin
Silvia L. Lage, Gustavo P. Amarante-Mendes, Karina R. Bortoluci
– Determination of apoptotic and necrotic cell death in vitro and in vivo
Tom Vanden Berghe, Sasker Grootjans, Vera Goossens, Yves Dondelinger, Dmitri V. Krysko, Nozomi Takahashi, Peter Vandenabeele
– Possible pitfalls investigating cell death responses in genetically engineered mouse models and derived cell lines
Claudia Manzl, Florian Baumgartner, Lukas Peintner, Fabian Schuler, Andreas Villunger
– Flow cytometry based assays for the measurement of apoptosis-associated mitochondrial membrane depolarisation and cytochrome c release
Melinda E. Christensen, Elisa S. Jansen, Washington Sanchez, Nigel J. Waterhouse
– BAK/BAX activation and cytochrome c release assays using isolated mitochondria
Thibaud T. Renault, Konstantinos V. Floros, Jerry E. Chipuk
– BH3 profiling in whole cells by fluorimeter or FACS
Jeremy Ryan, Anthony Letai
– Systems modelling methodology for the analysis of apoptosis signal transduction and cell death decisions
Markus Rehm, Jochen H.M. Prehn
– Methods for detection and analysis of apoptosis signaling in the C. elegans germline
Benjamin Lant, W. Brent Derry

—————————————————————————————————————————————-
—————————————————————————————————————————————-
—————————————————————————————————————————————-

Posted in Uncategorized | Leave a Comment »