Apolist – march 2012

Bcl-2 family members
Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
J.E. Chipuk, G.P. McStay, A. Bharti, T. Kuwana, C.J. Clarke, L.J. Siskind, L.M. Obeid, and D.R. Green
Differences in the Mechanisms of Proapoptotic BH3 Proteins Binding to Bcl-XL and Bcl-2 Quantified in Live MCF-7 Cells
A. Aranovich, Q. Liu, T. Collins, F. Geng, S. Dixit, B. Leber, and D.W. Andrews
Bax dimerizes via a symmetric BH3:groove interface during apoptosis
G Dewson, S Ma, P Frederick, C Hockings, I Tan, T Kratina and R M Kluck
Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization
Yuan-Ping Pang, Haiming Dai, Alyson Smith, X. Wei Meng, Paula A. Schneider & Scott H. Kaufmann
Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death
J J Sandow, A M Jabbour, M R Condina, C P Daunt, F C Stomski, B D Green, C D Riffkin, P Hoffmann, M A Guthridge, J Silke, A F Lopez and P G Ekert
Genetically defining the mechanism of Puma- and Bim-induced apoptosis
S P Garrison, D C Phillips, J R Jeffers, J E Chipuk, M J Parsons, J E Rehg, J T Opferman, D R Green and G P Zambetti
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX
Ryan E Henry, Zdenek Andrysik1, Ramiro París1,2, Matthew D Galbraith1 and Joaquín M Espinosa
Pharmacological blockade of Bcl-2, Bcl-xL and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice
S Grabow, P Waring, L Happo, M Cook, K D Mason, P N Kelly and A Strasser
Molecular basis of the interaction between the pro apoptotic tBID protein and mitochondrial carrier homologue 2 (MTCH2): Key players in the mitochondrial death pathway
Chen Katz, Yehudit Zaltsman-Amir, Yana Mostizky, Neta Kollet, Atan Gross, and Assaf Friedler
J. Biol. Chem. published 13 March 2012, 10.1074/jbc.M111.328377
Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function
Pedro Eitz Ferrer, Paul Frederick, Jacqueline M. Gulbis, Grant Dewson, Ruth M. Kluck
Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling
Cecilia Garcia-Perez, Soumya Sinha Roy, Shamim Naghdi, Xuena Lin, Erika Davies, and György Hajnóczky
Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays
C Wong, D J Anderson, E F Lee, W D Fairlie and M J C Ludlam
Death receptors and IAPs
Cellular Inhibitors of Apoptosis Are Global Regulators of NF-κB and MAPK Activation by Members of the TNF Family of Receptors
Eugene Varfolomeev, Tatiana Goncharov, Heather Maecker, Kerry Zobel, László G. Kömüves, Kurt Deshayes, Domagoj Vucic
Proteasome inhibition can impair caspase-8 Activation upon sub-maximal Stimulation of apoptotic tumour necrosis factor-related apoptosis inducing ligand (TRAIL) signalling
Maike A. Laussmann, Egle Passante, Christian T. Hellwig, Bartlomiej Tomiczek, Lorna Flanagan, Jochen H. M. Prehn, Heinrich J. Huber, and Markus Rehm
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
K Fu, H Ren, Y Wang, E Fei, H Wang and G Wang
Recognition of Human Tumor Necrosis Factor α (TNF-α) by Therapeutic Antibody Fragment: ENERGETICS AND STRUCTURAL FEATURES
Jaka Marusic, Crtomir Podlipnik, Simona Jevsevar, Drago Kuzman, Gorazd Vesnaver, and Jurij Lah
Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy
Perpetua U. Emeagi, Sandra Van Lint, Cleo Goyvaerts, Sarah Maenhout, Anje Cauwels, Iain A. McNeish, Tomas Bos, Carlo Heirman, Kris Thielemans, Joeri L. Aerts, and Karine Breckpot
Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells
C Jennewein, S Karl, B Baumann, O Micheau, K-M Debatin and S Fulda
Oxidatively truncated phospholipids are required agents of TNFα induced apoptosis
Calivarathan Latchoumycandane, Gopal K. Marathe, Renliang Zhang, and Thomas M. McIntyre
Caspases and phagocytosis
Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA
K Eto, S Goto, W Nakashima, Y Ura and S-I Abe
Tumor-suppressing function of caspase-2 requires catalytic site C320 and site S139 in mice
Keqin Ren, Jing Lu, Aleksey Porollo, and Chunying Du
Inhibitory mechanism of caspase-6 phosphorylation revealed by crystal structures, molecular dynamics (MD) simulations and biochemical assays
Qin Cao, Xiao-Jun Wang, Cheng-Wen Liu, Dai-Fei Liu, Lan-Fen Li, Yi-Qin Gao, and Xiao-Dong Su
Mechanism and specificity of the human paracaspase MALT1
Janna Hachmann, Scott J. Snipas, Bram J. van Raam, Erik M. Cancino, Emily J. Houlihan, Marcin Poreba, Paulina Kasperkiewicz, Marcin Drag and Guy S. Salvesen
Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis   
Giulio Preta, Bengt Fadeel
Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells
Venkateswara R. Simhadri, John F. Andersen, Eric Calvo, Seung-Chul Choi, John E. Coligan, and Francisco Borrego
Involvement of Beclin 1 in the engulfment of apoptotic cells
Akimitsu Konishi, Satoko Arakawa, Zhenyu Yue, and Shigeomi Shimizu
Alternative pathway of cell death in Drosophila mediated by NF-B transcription factor Relish
Yashodhan Chinchore, Gloria F. Gerber, and Patrick J. Dolph
Two Programmed Cell Death Systems in Escherichia coli: An Apoptotic-Like Death Is Inhibited by the mazEF-Mediated Death Pathway
Ariel Erental, Idith Sharon, Hanna Engelberg-Kulka
FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade
S Wang, P Xia, L Shi and Z Fan
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
K. Shimada, T.R. Crother, J. Karlin, J. Dagvadorj, N. Chiba, S. Chen, V.K. Ramanujan, A.J. Wolf, L. Vergnes, D.M. Ojcius, A. Rentsendorj, M. Vargas, C. Guerrero, Y. Wang, K.A. Fitzgerald, D.M. Underhill, T. Town, and M. Arditi
Rsk-mediated phosphorylation and 14-3-3ε binding of Apaf-1 suppresses cytochrome c-induced apoptosis
Jiyeon Kim, Amanda B Parrish1,2, Manabu Kurokawa1, Kenkyo Matsuura1, Christopher D Freel1, Joshua L Andersen, Carrie E Johnson and Sally Kornbluth
Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expression of a Subset of NF-κB Target Genes
Süheda Erener, Virginie Pétrilli, Ingrid Kassner, Roberta Minotti, Rosa Castillo, Raffaella Santoro, Paul O. Hassa, Jürg Tschopp, and Michael O. Hottiger
Reviews / comments
Mitochondria and cell signalling
Stephen W. G. Tait and Douglas R. Green
Caspase cleavage of viral proteins, another way for viruses to make the best of apoptosis
A Richard and D Tulasne
Greasing the Path to BAX/BAK Activation
Emilie Hollville and Seamus J. Martin
Sphingolipids Lower the Death Threshold
Sphingolipids from other organellar membranes set the threshold for mitochondrial permeabilization leading to cell death.
Apoptosis: A lipid trigger of MOMP
Development: Leading a programmed death