Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for November, 2010

Apolist – october 2010

Posted by cris on November 1, 2010

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Caspases and execution phase
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Pannexin 1 channels mediate ‘find-me’ signal release and membrane
permeability during apoptosis
Faraaz B. Chekeni,Michael R. Elliott,Joanna K. Sandilos,Scott F.
Walk,Jason M. Kinchen,Eduardo R. Lazarowski,Allison J.
Armstrong,Silvia Penuela,Dale W. Laird,Guy S. Salvesen,Brant E.
Isakson,Douglas A. Bayliss& Kodi S. Ravichandran
http://www.nature.com/nature/journal/v467/n7317/abs/nature09413.html?lang=en

Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3
C. V. Srikanth,1,2,* Daniel M. Wall,1,3,* Ana Maldonado-Contreras,2
Hai Ning Shi,1 Daoguo Zhou,4 Zachary Demma,2 Karen L. Mumy,1,2 Beth A.
McCormick
http://www.sciencemag.org/cgi/content/abstract/330/6002/390

Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I
Penghua Wang, Alvaro Arjona, Yue Zhang, Hameeda Sultana, Jianfeng Dai,
Long Yang, Philippe M LeBlanc, Karine Doiron, Maya Saleh and Erol
Fikrig
http://www.nature.com/ni/journal/v11/n10/full/ni.1933.html

Activation of caspase-9, but not caspase-2 or caspase-8, is essential
for heat-induced apoptosis in jurkat cells
Shary N. Shelton, Cindy D. Dillard, and John D. Robertson
http://www.jbc.org/cgi/content/abstract/M110.167635v1

Crystal structures of human caspase 6 reveal a new mechanism for
intramolecular cleavage self-activation
Xiao-Jun Wang, Qin Cao, Xiang Liu, Kai-Tuo Wang, Wei Mi, Yan Zhang,
Lan-Fen Li, Andrea C LeBlanc and Xiao-Dong Su
http://www.nature.com/embor/journal/v11/n11/full/embor2010141.html

Real-Time Dynamics of Ca2+, Caspase-3/7, and Morphological Changes in
Retinal Ganglion Cell Apoptosis under Elevated Pressure
Jae Kyoo Lee, Siyuan Lu, Anupam Madhukar
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013437

Characterization of a caspase-3-substrate kinome using an N- and
C-terminally tagged protein kinase library produced by a cell-free
system
D Tadokoro, S Takahama, K Shimizu, S Hayashi, Y Endo and T Sawasaki
http://www.nature.com/cddis/journal/v1/n10/abs/cddis201065a.html

Mutant nucleophosmin deregulates cell death and myeloid
differentiation through excessive caspase-6 and -8 inhibition
Sai Mun Leong, Ban Xiong Tan, Baidah Bte Ahmad, Tie Yan, Lai Yuen
Chee, Swee Tin Ang, Kian Ghee Tay, Liang Piu Koh, Allen Eng Juh Yeoh,
Evelyn Siew-Chuan Koay, Yu-Keung Mok, and Tit Meng Lim
http://bloodjournal.hematologylibrary.org/cgi/content/abstract/116/17/3286

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Bcl-2 family proteins
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BH3-only protein Bmf mediates apoptosis upon inhibition of
CAP-dependent protein synthesis
F Grespi, C Soratroi, G Krumschnabel, B Sohm, C Ploner, S Geley, L
Hengst, G Häcker and A Villunger
http://www.nature.com/cdd/journal/v17/n11/full/cdd201097a.html

Parkin mono-ubiquitinates BCL-2 and regulates autophagy
Dong Chen, Feng Gao, Bin Li, Hongfeng Wang, Yuxia Xu, Cuiqing Zhu, and
Guanghui Wang
http://www.jbc.org/cgi/content/abstract/M110.101469v1

Bcl-2 inhibits apoptosis by increasing the time-to-death and intrinsic
cell-to-cell variations in the mitochondrial pathway of cell death
Joanna Skommer, Tom Brittain & Subhadip Raychaudhuri
http://www.springerlink.com/content/u21l21nu311nl2v7/

Mono- or Double-Site Phosphorylation Distinctly Regulates the
Proapoptotic Function of Bax
Qinhong Wang, Shi-Yong Sun, Fadlo Khuri, Walter J. Curran, Xingming Deng
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013393

The DNA damage response pathway regulates the alternative splicing of
the apoptotic mediator Bcl-x
Lulzim Shkreta, Laetitia Michelle, Johanne Toutant, Michel L.
Tremblay, and Benoit Chabot
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.162644
http://www.jbc.org/cgi/content/abstract/M110.162644v1

Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of
hematopoietic stem/progenitor cells, and enhances drug resistance
Kirsteen J. Campbell, Mary L. Bath, Marian L. Turner, Cassandra J.
Vandenberg, Philippe Bouillet, Donald Metcalf, Clare L. Scott, and
Suzanne Cory
http://bloodjournal.hematologylibrary.org/cgi/content/abstract/116/17/3197

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Death receptor pathway
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Caspase-10-Dependent Cell Death in Fas/CD95 Signalling Is Not
Abrogated by Caspase Inhibitor zVAD-fmk
Elodie Lafont, Delphine Milhas, Justin Teissié, Nicole Therville,
Nathalie Andrieu-Abadie, Thierry Levade, Hervé Benoist, Bruno Ségui
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013638

The Fas–FADD death domain complex structure reveals the basis of DISC
assembly and disease mutations
Liwei Wang,Jin Kuk Yang,Venkataraman Kabaleeswaran,Amanda J
Rice,Anthony C Cruz,Ah Young Park,Qian Yin,Ermelinda Damko,Se Bok
Jang,Stefan Raunser,Carol V Robinson,Richard M Siegel,Thomas Walz& Hao
Wu
http://www.nature.com/nsmb/journal/vaop/ncurrent/full/nsmb.1920.html

The inhibition of Bid expression by Akt leads to resistance to
TRAIL-induced apoptosis in ovarian cancer cells
N Goncharenko-Khaider, D Lane, I Matte, C Rancourt and A Piché
http://www.nature.com/onc/journal/v29/n40/full/onc2010288a.html

HDAC inhibitors with different gene regulation activities depend on
the mitochondrial pathway for the sensitization of leukemic T cells to
TRAIL-induced apoptosis
Morales, JC; Ruiz-Magana, MJ; Carranza, D; Ortiz-Ferron, G; Ruiz-Ruiz, C
http://dx.doi.org/10.1016/j.canlet.2010.04.029

Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting
Specifically Through the Caspase-8 Apoptotic Axis
Darren Finlay, Robyn D. Richardson, Lisa K. Landberg, Amy L. Howes,
Kristiina Vuori
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013375

Caspase cleavage of the Golgi stacking factor GRASP65 is required for
Fas/CD95-mediated apoptosis
J P X Cheng, V M S Betin, H Weir, G M A Shelmani, D K Moss and J D Lane
http://www.nature.com/cddis/journal/v1/n10/full/cddis201059a.html

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IAPS
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A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage
Signaling to Ubiquitin-Mediated NF-κB Activation
M. Hinz, M. Stilmann, S.Ç. Arslan, K.K. Khanna, G. Dittmar, and C. Scheidereit
http://www.cell.com/molecular-cell/abstract/S1097-2765%2810%2900710-0

Monomerization of Cytosolic Mature Smac Attenuates Interaction with
IAPs and Potentiation of Caspase Activation
Stephen P. Burke, Jeffrey B. Smith
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013094

Smac mimetic compounds potentiate interleukin-1 beta-mediated cell death
Herman H. Cheung, Shawn T. Beug, Martine St. Jean, Audrey Brewster, N.
Lynn Kelly, Shaomeng Wang, and Robert G. Korneluk
J. Biol. Chem. published 18 October 2010, 10.1074/jbc.M110.183616
http://www.jbc.org/cgi/content/abstract/M110.183616v1

Mitochondrial fission leads to Smac/DIABLO release quenched by ARC
Jincheng Li, Yanrui Li, Danian Qin, Ruediger von Harsdorf & Peifeng Li
http://www.springerlink.com/content/nj77723m68242817/

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Miscellaneous
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NF- B inhibits T-cell activation-induced, p73-dependent cell death by
induction of MDM2
Valere Busuttil, Nathalie Droin, Laura McCormick, Francesca
Bernassola, Eleonora Candi, Gerry Melino, and Douglas R. Green
http://www.pnas.org/content/107/42/18061.abstract?etoc

Sphingolipid-mediated inhibition of apoptotic cell clearance by
alveolar macrophages
Daniela N. Petrusca, Yuan Gu, Jeremy J. Adamowicz, Natalia I. Rush,
Walter C. Hubbard, Patricia A. Smith, Evgeny V. Berdyshev, Konstantin
G. Birukov, Chao-Hung Lee, Rubin M. Tuder, Homer L. Twigg IIIrd, R.
William Vandivier, and Irina Petrache
http://www.jbc.org/cgi/content/abstract/M110.137604v1

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REVIEWS / Comments
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Sugar-free approaches to cancer cell killing.
Nadia El Mjiyad, Alfredo Caro-Maldonado, Silvia Ramírez-Peinado, Cristina Muñoz-Pinedo
http://www.nature.com/onc/journal/vaop/ncurrent/full/onc2010466a.html

Molecular mechanisms of necroptosis: an ordered cellular explosion
Peter Vandenabeele, Lorenzo Galluzzi, Tom Vanden Berghe & Guido Kroemer
http://www.nature.com/nrm/journal/v11/n10/full/nrm2970.html

Systems biology analysis of programmed cell death
Shani Bialik, Einat Zalckvar, Yaara Ber, Assaf D. Rubinstein, Adi Kimchi
http://dx.doi.org/10.1016/j.tibs.2010.04.008

Apoptotic volume decrease as a geometric determinant for cell
dismantling into apoptotic bodies
R Núñez, S M Sancho-Martínez, J M L Novoa and F J López-Hernández
http://www.nature.com/cdd/journal/v17/n11/abs/cdd201096a.html

Apoptosis, Stem Cells, and Tissue Regeneration
Andreas Bergmann and Hermann Steller
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/145/re8?etoc

The engine driving the ship: metabolic steering of cell proliferation and death
Marisa R. Buchakjian & Sally Kornbluth
http://www.nature.com/nrm/journal/v11/n10/full/nrm2972.html

Channeling Death
Wei Wong
Apoptotic cells release ATP and UTP through pannexin 1 to recruit
phagocytes that clear them.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/144/ec318?etoc

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