Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for October, 2010

Apolist – september 2010

Posted by cris on October 3, 2010

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Bcl-2 family proteins
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Membrane Remodeling Induced by the Dynamin-Related Protein Drp1
Stimulates Bax Oligomerization
S. Montessuit, S.P. Somasekharan, O. Terrones, S. Lucken-Ardjomande,
S. Herzig, R. Schwarzenbacher, D.J. Manstein, E. Bossy-Wetzel, G.
Basañez, P. Meda, and J.-C. Martinou
http://www.cell.com/abstract/S0092-8674(10)00948-7

Displacement of Bim by Bmf and Puma rather than increase in Bim level
mediates paclitaxel-induced apoptosis in breast cancer cells
O Kutuk and A Letai
http://www.nature.com/cdd/journal/v17/n10/full/cdd201041a.html

Individual and overlapping roles of BH3-only proteins Bim and Bad in
apoptosis of lymphocytes and platelets and in suppression of thymic
lymphoma development
P N Kelly, M J White, M W Goschnick, K A Fairfax, D M Tarlinton, S A
Kinkel, P Bouillet, J M Adams, B T Kile and A Strasser
http://www.nature.com/cdd/journal/v17/n10/full/cdd201043a.html

INHIBITION OF BAK ACTIVATION BY VDAC2 IS DEPENDENT ON THE BAK
TRANSMEMBRANE ANCHOR
Michael Lazarou, Diana Stojanovski, Ann E. Frazier, Aneta Kotevski,
Grant Dewson, William J Craigen, Ruth M. Kluck, David L. Vaux, and
Michael T. Ryan
http://www.jbc.org/cgi/content/abstract/M110.159301v1

The BH3-only protein Bad confers breast cancer taxane sensitivity
through a nonapoptotic mechanism
A C Craik, R A Veldhoen, M Czernick, T W Buckland, K Kyselytzia, S
Ghosh, R Lai, S Damaraju, D A Underhill, J R Mackey and I S Goping
http://www.nature.com/onc/journal/v29/n39/abs/onc2010272a.html

Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor
Alexander H. Stegh, Cameron Brennan, John A. Mahoney, Kristin L. Forloney, Harry
T. Jenq, Janina P. Luciano, Alexei Protopopov, Lynda Chin, and Ronald
A. DePinho
http://genesdev.cshlp.org/cgi/content/abstract/24/19/2194

BAX insertion, oligomerization, and outer membrane permeabilization in
brain mitochondria: Role of permeability transition and SH-redox
regulation
Tatiana Brustovetsky, Tsyregma Li, Youyun Yang, Jiang-Ting Zhang,
Bruno Antonsson, Nickolay Brustovetsky
http://dx.doi.org/10.1016/j.bbabio.2010.07.006

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Death receptors and IAPs
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Smac/DIABLO release from mitochondria and XIAP inhibition are
essential to limit clonogenicity of Type I tumor cells after TRAIL
receptor stimulation
C Maas, I Verbrugge, E de Vries, G Savich, L W van de Kooij, S W G
Tait and J Borst
http://www.nature.com/cdd/journal/v17/n10/full/cdd201039a.html

Smac mimetics increase cancer cell response to chemotherapeutics in a
TNF-α-dependent manner
B L Probst, L Liu, V Ramesh, L Li, H Sun, J D Minna and L Wang
http://www.nature.com/cdd/journal/v17/n10/full/cdd201044a.html

TRAIL treatment provokes mutations in surviving cells
M M Lovric and C J Hawkins
http://www.nature.com/onc/journal/v29/n36/abs/onc2010242a.html

Drosophila IAP antagonists form multimeric complexes to promote cell death
Cristinel Sandu, Hyung Don Ryoo, and Hermann Steller
http://jcb.rupress.org/cgi/content/abstract/190/6/1039?etoc

IAP inhibitors enhance co-stimulation to promote tumor immunity
Michael Dougan, Stephanie Dougan, Joanna Slisz, Brant Firestone,
Matthew Vanneman, Dobrin Draganov, Girija Goyal, Weibo Li, Donna
Neuberg, Richard Blumberg, Nir Hacohen, Dale Porter, Leigh Zawel, and
Glenn Dranoff
http://jem.rupress.org/cgi/content/abstract/207/10/2195?etoc

Characterization of the Extrinsic Apoptotic Pathway in the Basal
Chordate Amphioxus
Shaochun Yuan, Huiling Liu, Ming Gu, Liqun Xu, Shengfeng Huang,
Zhenhua Ren, and Anlong Xu
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/139/ra66?etoc

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Caspases and downstream
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Metabolic regulation of Drosophila apoptosis through inhibitory
phosphorylation of Dronc
Chih-Sheng Yang, Michael J Thomenius, Eugene C Gan, Wanli Tang,
Christopher D Freel, Thomas J S Merritt, Leta K Nutt and Sally
Kornbluth
http://www.nature.com/emboj/journal/v29/n18/full/emboj2010191a.html

Discovery and Canine Preclinical Assessment of a Nontoxic
Procaspase-3–Activating Compound
Quinn P. Peterson, Danny C. Hsu, Chris J. Novotny, Diana C. West,
Dewey Kim, Joanna M. Schmit, Levent Dirikolu, Paul J. Hergenrother,
and Timothy M. Fan
http://cancerres.aacrjournals.org/cgi/content/abstract/70/18/7232

Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo
Michael R. Elliott1,2, Shuqiu Zheng3, Daeho Park1,2, Robin I.
Woodson3, Michael A. Reardon3, Ignacio J. Juncadella1,2, Jason M.
Kinchen2,4, Jun Zhang3, Jeffrey J. Lysiak2,3,5 & Kodi S. Ravichandran
http://www.nature.com/nature/journal/v467/n7313/full/nature09356.html

Decrease of sialic acid residues as an eat-me signal on the surface of
apoptotic lymphocytes
Hanna Marie Meesmann, Eva-Marie Fehr, Sonja Kierschke, Martin
Herrmann, Rostyslav Bilyy, Petra Heyder, Norbert Blank, Stefan
Krienke, Hanns-Martin Lorenz, and Martin Schiller
J Cell Sci 2010;123 3347-3356
http://jcs.biologists.org/cgi/content/abstract/123/19/3347

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MISCELLANEOUS
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Cathepsin B-like and cell death in the unicellular human pathogen Leishmania
A K El-Fadili, H Zangger, C Desponds, I J Gonzalez, H Zalila, C
Schaff, A Ives, S Masina, J C Mottram and N Fasel
http://www.nature.com/cddis/journal/v1/n9/full/cddis201051a.html

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
D Tang, R Kang, C-W Cheh, K M Livesey, X Liang, N E Schapiro, R
Benschop, L J Sparvero, A A Amoscato, K J Tracey, H J Zeh and M T
Lotze
http://www.nature.com/onc/journal/v29/n38/full/onc2010261a.html

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REVIEWS / COMMENTS
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Apoptosis:
Special Issue on Clearance of Dead Cells: Mechanisms, Immune Responses
and Implication in the Development of Diseases.
Editors: Dmitri V. Krysko and Peter Vandenabeele
http://www.springerlink.com/content/1360-8185/15/9/

Regulation of the Apaf-1–caspase-9 apoptosome
Shawn B. Bratton and Guy S. Salvesen
http://jcs.biologists.org/cgi/content/full/123/19/3209

The Hydra model: disclosing an apoptosis-driven generator of Wnt-based
regeneration
Brigitte Galliot, Simona Chera
http://www.cell.com/trends/cell-biology/abstract/S0962-8924(10)00099-1

Still embedded together binding to membranes regulates Bcl-2 protein
interactions
B Leber, J Lin and D W Andrews
http://www.nature.com/onc/journal/v29/n38/full/onc2010283a.html

Sweetening apoptotic-cell engulfment
J Cell Sci 2010;123 e1902
http://jcs.biologists.org/cgi/content/full/123/19/e1902




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