Apoptosis and cell death

Apolist: monthly literature updates for researchers

Archive for July, 2010

Apolist – July 2010

Posted by cris on July 26, 2010

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Bcl-2 family members
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Phosphorylation of Mcl-1 by CDK1–cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest
Margaret E Harley, Lindsey A Allan, Helen S Sanderson and Paul R Clarke
http://www.nature.com/emboj/journal/v29/n14/abs/emboj2010112a.html

Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3:BH3 contact interface in BAK homooligomers
Kyoung Joon Oh, Pawan Singh, Kyungro Lee, Kelly Foss, Shinyoub Lee, Minji Park, Steffi Lee, Sreevidya Aluvila, Matthew Park, Puja Singh, Ryung-Suk Kim, Jindrich Smyersky, and D. Eric Walters
http://www.jbc.org/cgi/content/abstract/M110.135293v1

TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1
J K Son, S Varadarajan and S B Bratton
http://www.nature.com/cdd/journal/v17/n8/full/cdd20109a.html

Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization
O. Jameel Shah, Xiaoyu Lin, Leiming Li, Xiaoli Huang, Junling Li, Mark G. Anderson, Hua Tang, Luis E. Rodriguez, Scott E. Warder, Shaun McLoughlin, Jun Chen, Joann Palma, Keith B. Glaser, Cherrie K. Donawho, Stephen W. Fesik, and Yu Shen
http://www.pnas.org/content/107/28/12634.abstract?etoc

Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes
Jeremy A. Ryan, Joslyn K. Brunelle, and Anthony Letai
http://www.pnas.org/content/107/29/12895.abstract?etoc

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Death receptors and caspases
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Fas-associated death domain (FADD) is a negative regulator of T-cell receptor–mediated necroptosis
Stephanie L. Osborn, Gretchen Diehl, Seong-Ji Han, Ling Xue, Nadia Kurd, Kristina Hsieh, Dragana Cado, Ellen A. Robey, and Astar Winoto
http://www.pnas.org/content/107/29/13034.abstract?etoc

Oncogenic Ras Diverts a Host TNF Tumor Suppressor Activity into Tumor Promoter
J.B. Cordero, J.P. Macagno, R.K. Stefanatos, K.E. Strathdee, R.L. Cagan, and M. Vidal
http://www.cell.com/developmental-cell/abstract/S1534-5807%2810%2900250-9

Gradients of a Ubiquitin E3 Ligase Inhibitor and a Caspase Inhibitor Determine Differentiation or Death in Spermatids
Y. Kaplan, L. Gibbs-Bar, Y. Kalifa, Y. Feinstein-Rotkopf, and E. Arama
http://www.cell.com/developmental-cell/abstract/S1534-5807%2810%2900299-6

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Miscellaneous
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From the Cover: Biophotonic probing of macromolecular transformations during apoptosis
Artem Pliss, Andrey N. Kuzmin, Aliaksandr V. Kachynski, and Paras N. Prasad
http://www.pnas.org/content/107/29/12771.abstract?etoc

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction
Sanjeev Gupta, Ayswaria Deepti, Shane Deegan, Fernanda Lisbona, Claudio Hetz, Afshin Samali
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000410

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Reviews
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IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
Mads Gyrd-Hansen & Pascal Meier
http://www.nature.com/nrc/journal/v10/n8/full/nrc2889.html

Intertwined pathways of programmed cell death in immunity
Stephen M. Hedrick 1 , Irene L. Ch’en 1 , Bryce N. Alves
http://www3.interscience.wiley.com/cgi-bin/fulltext/123526684/HTMLSTART

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death.
Montero J, Mari M, Colell A, Morales A, Basañez G, Garcia-Ruiz C, Fernández-Checa JC.
http://dx.doi.org/10.1016/j.bbabio.2010.02.010

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Comments
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Metacaspases are not caspases – always doubt
M Enoksson and G S Salvesen
http://www.nature.com/cdd/journal/v17/n8/full/cdd201045a.html

Paradise revealed: first-class science rocked by the sound of the waves
G P Amarante-Mendes, K R Bortoluci, P T Bozza, R Chammas and J P B Viola
http://www.nature.com/cdd/journal/v17/n8/abs/cdd201066a.html

Stalling in mitosis and releasing the apoptotic brake
Manabu Kurokawa and Sally Kornbluth
http://www.nature.com/emboj/journal/v29/n14/full/emboj2010150a.html

———————–

Bcl-2 family members

———————–

Phosphorylation of Mcl-1 by CDK1–cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest

Margaret E Harley, Lindsey A Allan, Helen S Sanderson and Paul R Clarke

http://www.nature.com/emboj/journal/v29/n14/abs/emboj2010112a.html

Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3:BH3 contact interface in BAK homooligomers

Kyoung Joon Oh, Pawan Singh, Kyungro Lee, Kelly Foss, Shinyoub Lee, Minji Park, Steffi Lee, Sreevidya Aluvila, Matthew Park, Puja Singh, Ryung-Suk Kim, Jindrich Smyersky, and D. Eric Walters

http://www.jbc.org/cgi/content/abstract/M110.135293v1

TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1

J K Son, S Varadarajan and S B Bratton

http://www.nature.com/cdd/journal/v17/n8/full/cdd20109a.html

Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization

O. Jameel Shah, Xiaoyu Lin, Leiming Li, Xiaoli Huang, Junling Li, Mark G. Anderson, Hua Tang, Luis E. Rodriguez, Scott E. Warder, Shaun McLoughlin, Jun Chen, Joann Palma, Keith B. Glaser, Cherrie K. Donawho, Stephen W. Fesik, and Yu Shen

http://www.pnas.org/content/107/28/12634.abstract?etoc

Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes

Jeremy A. Ryan, Joslyn K. Brunelle, and Anthony Letai

http://www.pnas.org/content/107/29/12895.abstract?etoc

——————————

Death receptors and caspases

——————————

Fas-associated death domain (FADD) is a negative regulator of T-cell receptor–mediated necroptosis

Stephanie L. Osborn, Gretchen Diehl, Seong-Ji Han, Ling Xue, Nadia Kurd, Kristina Hsieh, Dragana Cado, Ellen A. Robey, and Astar Winoto

http://www.pnas.org/content/107/29/13034.abstract?etoc

Oncogenic Ras Diverts a Host TNF Tumor Suppressor Activity into Tumor Promoter

J.B. Cordero, J.P. Macagno, R.K. Stefanatos, K.E. Strathdee, R.L. Cagan, and M. Vidal

http://www.cell.com/developmental-cell/abstract/S1534-5807%2810%2900250-9

Gradients of a Ubiquitin E3 Ligase Inhibitor and a Caspase Inhibitor Determine Differentiation or Death in Spermatids

Y. Kaplan, L. Gibbs-Bar, Y. Kalifa, Y. Feinstein-Rotkopf, and E. Arama

http://www.cell.com/developmental-cell/abstract/S1534-5807%2810%2900299-6

————–

Miscellaneous

————–

From the Cover: Biophotonic probing of macromolecular transformations during apoptosis

Artem Pliss, Andrey N. Kuzmin, Aliaksandr V. Kachynski, and Paras N. Prasad

http://www.pnas.org/content/107/29/12771.abstract?etoc

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

Sanjeev Gupta, Ayswaria Deepti, Shane Deegan, Fernanda Lisbona, Claudio Hetz, Afshin Samali

http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000410

———

Reviews

———

IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer

Mads Gyrd-Hansen & Pascal Meier

http://www.nature.com/nrc/journal/v10/n8/full/nrc2889.html

Intertwined pathways of programmed cell death in immunity

Stephen M. Hedrick 1 , Irene L. Ch’en 1 , Bryce N. Alves

http://www3.interscience.wiley.com/cgi-bin/fulltext/123526684/HTMLSTART

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death.

Montero J, Mari M, Colell A, Morales A, Basañez G, Garcia-Ruiz C, Fernández-Checa JC.

http://dx.doi.org/10.1016/j.bbabio.2010.02.010

———–

Comments

———–

Metacaspases are not caspases – always doubt

M Enoksson and G S Salvesen

http://www.nature.com/cdd/journal/v17/n8/full/cdd201045a.html

Paradise revealed: first-class science rocked by the sound of the waves

G P Amarante-Mendes, K R Bortoluci, P T Bozza, R Chammas and J P B Viola

http://www.nature.com/cdd/journal/v17/n8/abs/cdd201066a.html

Stalling in mitosis and releasing the apoptotic brake

Manabu Kurokawa and Sally Kornbluth

http://www.nature.com/emboj/journal/v29/n14/full/emboj2010150a.html

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Apolist – june 2010

Posted by cris on July 9, 2010

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Bcl-2 family proteins
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Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones
F.M. Wensveen, K.P.J.M. van Gisbergen, I.A.M. Derks, C. Gerlach, T.N. Schumacher, R.A.W. van Lier, and E. Eldering
http://www.cell.com/immunity/abstract/S1074-7613%2810%2900208-6

Growth factor stimulation induces cell survival by C-jun/ATF2-dependent activation of BCL-XL
Ahmad Salameh, Federico Galvagni, Francesca Anselmi, Caterina De Clemente, Maurizio Orlandini, and Salvatore Oliviero
J. Biol. Chem. published 27 May 2010, 10.1074/jbc.M109.087221
http://www.jbc.org/cgi/content/abstract/M109.087221v1

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications
Zhi Sheng, Li Li, Lihua J Zhu, Thomas W Smith, Andrea Demers, Alonzo H Ross, Richard P Moser and Michael R Green
http://www.nature.com/nm/journal/v16/n6/full/nm.2158.html

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells
A Greenhough, C A Wallam, D J Hicks, M Moorghen, A C Williams and C Paraskeva
http://www.nature.com/onc/journal/v29/n23/full/onc201094a.html

Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
Lijian Shao, Yan Sun, Zhonghui Zhang, Wei Feng, Yongxing Gao, Zailong Cai, Zack Z. Wang, A. Thomas Look, and Wen-Shu Wu
Blood 2010;115 4707-4714
http://bloodjournal.hematologylibrary.org/cgi/content/abstract/115/23/4707

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
Emma M. Carrington, Ingela B. Vikstrom, Amanda Light, Robyn M. Sutherland, Sarah L. Londrigan, Kylie D. Mason, David C. S. Huang, Andrew M. Lew, and David M. Tarlinton
http://www.pnas.org/content/107/24/10967.abstract?etoc

The BH3-mimetic gossypol induces both beclin 1-dependent and beclin 1-independent cytoprotective autophagy in cancer cells
Ping Gao, Chantal Bauvy, Sylvie Souquere, Giovanni Tonelli, Lei Liu, Yushan Zhu, Zhenzhen Qiao, Daniela Bakula, Tassula Proikas-Cezanne, Gerard Pierron, Patrice Codogno, Quan Chen, and Maryam Mehrpour
J. Biol. Chem. published 7 June 2010, 10.1074/jbc.M110.118125
http://www.jbc.org/cgi/content/abstract/M110.118125v1

BCL-2 and bax interact via the BH1-3 groove:BH3 motif interface and a novel interface involving the BH4 motif
Jingzhen Ding, Zhi Zhang, G. Jane Roberts, Mina Falcone, Yiwei Miao, Yuanlong Shao, Xuejun C. Zhang, David W. Andrews, and Jialing Lin
J. Biol. Chem. published 28 June 2010, 10.1074/jbc.M110.148361
http://www.jbc.org/cgi/content/abstract/M110.148361v1

High-Mobility Group A1 Proteins Regulate p53-Mediated Transcription of Bcl-2 Gene
Francesco Esposito, Mara Tornincasa, Paolo Chieffi, Ivana De Martino, Giovanna Maria Pierantoni, and Alfredo Fusco
Cancer Res 2010;70 5379-5388
http://cancerres.aacrjournals.org/cgi/content/abstract/70/13/5379

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Death receptors and IAPs
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XIAP impairs Smac release from the mitochondria during apoptosis
L Flanagan, J Sebastià, L P Tuffy, A Spring, A Lichawska, M Devocelle, J H M Prehn and M Rehm
http://www.nature.com/cddis/journal/v1/n6/full/cddis201026a.html

FADD-calmodulin interaction: A novel player in cell cycle regulation
Pages 898-911
Giuliana Papoff, Nadia Trivieri, Roberta Crielesi, Francesca Ruberti, Sonia Marsilio, Giovina Ruberti
http://dx.doi.org/10.1016/j.bbamcr.2010.04.006

Effective Blockage of Both the Extrinsic and Intrinsic Pathways of Apoptosis in Mice by TAT-crmA
Stefan Krautwald, Ekkehard Ziegler, Lars Rölver, Andreas Linkermann, Kirsten A. Keyser, Philip Steen, Kai C. Wollert, Mortimer Korf-Klingebiel, and Ulrich Kunzendorf
http://www.jbc.org/content/285/26/19997.abstract?etoc

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Sergio E. Alvarez, Kuzhuvelil B. Harikumar,Nitai C. Hait,Jeremy Allegood,Graham M. Strub,Eugene Y. Kim,Michael Maceyka,Hualiang Jiang, Cheng Luo, Tomasz Kordula, Sheldon Milstien & Sarah Spiegel
http://www.nature.com/nature/journal/v465/n7301/full/nature09128.html

mir-200c Regulates Induction of Apoptosis through CD95 by Targeting FAP-1
R. Schickel, S.-M. Park, A.E. Murmann, and M.E. Peter
http://www.cell.com/molecular-cell/abstract/S1097-2765%2810%2900380-1

Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression
Sean L. Petersen, Michael Peyton, John D. Minna, and Xiaodong Wang
http://www.pnas.org/content/107/26/11936.abstract?etoc

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Miscellaneous
————————-

Activation of autophagy during cell death requires the engulfment receptor Draper
Christina K. McPhee, Mary A. Logan, Marc R. Freeman and Eric H. Baehrecke
http://www.nature.com/nature/journal/v465/n7301/full/nature09127.html

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes
C Oberle, J Huai, T Reinheckel, M Tacke, M Rassner, P G Ekert, J Buellesbach and C Borner
http://www.nature.com/cdd/journal/v17/n7/full/cdd2009214a.html

Oncogene-Induced Sensitization to Chemotherapy-Induced Death Requires Induction as well as Deregulation of E2F1
G. Vignir Helgason, Jim O’Prey, and Kevin M. Ryan
Cancer Res 2010;70 4074-4080
http://cancerres.aacrjournals.org/cgi/content/abstract/70/10/4074

Identification of functional regions defining different activity between caspase-3 and caspase-7 within cells
Hirokazu Nakatsumi and Shin Yonehara
J. Biol. Chem. published 21 June 2010, 10.1074/jbc.M110.126573
http://www.jbc.org/cgi/content/abstract/M110.126573v1

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REVIEWS / COMMENTS
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Bcl-2-regulated cell death signalling in the prevention of autoimmunity
D Tischner, C Woess, E Ottina and A Villunger
http://www.nature.com/cddis/journal/v1/n6/full/cddis201027a.html

The role of caspase-2 in stress-induced apoptosis
Lisa Bouchier-Hayes
http://www3.interscience.wiley.com/journal/123286432/abstract

Neuronal caspase-3 signaling: not only cell death
M D’Amelio, V Cavallucci and F Cecconi
http://www.nature.com/cdd/journal/v17/n7/full/cdd2009180a.html

Clearance of apoptotic cells: implications in health and disease
Michael R. Elliott and Kodi S. Ravichandran
http://jcb.rupress.org/cgi/content/abstract/189/7/1059?etoc

Only the Strong Survive
A. Villunger
http://www.cell.com/immunity/abstract/S1074-7613%2810%2900213-X

Depressed About Caspases?
Elizabeth M. Adler
Sci. Signal. 3 (125), ec170. [DOI: 10.1126/scisignal.3125ec170]
Elements of the mitochondrial apoptosis pathway are used to mediate long-term depression of synaptic function.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/125/ec170?etoc

Posted in apoptosis literature | 1 Comment »