Glucose metabolism attenuates p53 and puma-dependent cell death upon growth factor deprivation
Yuxing Zhao, Jonathan L. Coloff, Emily C. Ferguson, Sarah R. Jacobs, Kai Cui, and Jeffrey C. Rathmell
J. Biol. Chem. published 6 November 2008, 10.1074/jbc.M803580200
http://www.jbc.org/cgi/content/abstract/M803580200v1
Ceramide starves cells to death by downregulating nutrient transporter proteins
Garret G. Guenther, Eigen R. Peralta, Kimberly Romero Rosales, Susan Y. Wong, Leah J. Siskind, and Aimee L. Edinger
http://www.pnas.org/content/105/45/17402.abstract?etoc
FKBP36 is an inherent multi-functional glyceraldehyde-3-phosphate dehydrogenase inhibitor
Franziska Jarczowski, Günther Jahreis, Frank Erdmann, Angelika Schierhorn, Gunter Fischer, and Frank Edlich
J. Biol. Chem. published 10 November 2008, 10.1074/jbc.M709779200
http://www.jbc.org/cgi/content/abstract/M709779200v1
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Andrew Y. Choo, Sang-Oh Yoon, Sang Gyun Kim, Philippe P. Roux, and John Blenis
http://www.pnas.org/content/105/45/17414.abstract?etoc
Peptide combinatorial libraries Identify TSC2 as a DAPK death domain binding protein and reveal a stimulatory role for DAPK in mTORC1 signalling
Craig Stevens, Yao Lin, Ben Harrison, Lindsay Burch, Rachel A. Ridgway, Owen Sansom, and Ted Hupp
http://www.jbc.org/cgi/content/abstract/M805165200v1
A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death
Wood, T. E., Dalili, S., Simpson, C. D., Hurren, R., Mao, X., Saiz, F. S., Gronda, M., Eberhard, Y., Minden, M. D., Bilan, P. J., Klip, A., Batey, R. A., Schimmer, A. D.
http://mct.aacrjournals.org/cgi/content/full/7/11/3546?ct
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim, Pankuri Goraksha-Hicks, Li Li, Thomas P. Neufeld and Kun-Liang Guan
http://www.nature.com/ncb/journal/v10/n8/full/ncb1753.html
Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2
Deidre Jansson, Andy Cheuk-Him Ng, Accalia Fu, Chantal Depatie, Mufida Al Azzabi, and Robert A. Screaton
http://www.pnas.org/content/105/29/10161.abstract?etoc
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
I Papandreou, A L Lim, K Laderoute & N C Denko
http://www.nature.com/cdd/journal/v15/n10/full/cdd200884a.html
Inactivation of the CYLD Deubiquitinase by HPV E6 Mediates Hypoxia-Induced NF-κB Activation
J. An, D. Mo, H. Liu, M.S. Veena, E.S. Srivatsan, R. Massoumi, and M.B. Rettig
http://www.cell.com/cancer-cell/abstract/S1535-6108%2808%2900331-0
A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism
Daniel Moreno, Erwin Knecht, Benoit Viollet and Pascual Sanz
http://dx.doi.org/10.1016/j.febslet.2008.06.044
AMP-Activated Protein Kinase Signaling Results in Cytoplasmic Sequestration of p27
John D. Short, Kevin D. Houston, Ruhee Dere, Sheng-Li Cai, Jinhee Kim, Charles L. Johnson, Russell R. Broaddus, Jianjun Shen, Susie Miyamoto, Fuyuhiko Tamanoi, David Kwiatkowski, Gordon B. Mills, and Cheryl Lyn Walker
http://cancerres.aacrjournals.org/cgi/content/abstract/68/16/6496
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
T. Porstmann, C.R. Santos, B. Griffiths, M. Cully, M. Wu, S. Leevers, J.R. Griffiths, Y.-L. Chung, and A. Schulze
http://www.cellmetabolism.org/content/article/abstract?uid=PIIS1550413108002398
Inhibition of fatty acid synthase induces caspase 8-mediated tumor cell apoptosis by Up-regulating DDIT4
Lynn M. Knowles, Chen Yang, Andrei Osterman, and Jeffrey W. Smith
http://www.jbc.org/cgi/content/abstract/M803384200v1
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Michael Degtyarev, Ann De Mazière, Christine Orr, Jie Lin, Brian B. Lee, Janet Y. Tien, Wei W. Prior, Suzanne van Dijk, Hong Wu, Daniel C. Gray, David P. Davis, Howard M. Stern, Lesley J. Murray, Klaus P. Hoeflich, Judith Klumperman, Lori S. Friedman, and Kui Lin
http://www.jcb.org/cgi/content/abstract/183/1/101?etoc
METHODS
Chapter Twenty-Two
Mechanisms and Methods in Glucose Metabolism and Cell Death
Yuxing Zhao, Heather L. Wieman, Sarah R. Jacobs, Jeffrey C. Rathmell
http://dx.doi.org/10.1016/S0076-6879(08)01422-5
REVIEWS / COMMENTS
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Nicholas C. Denko
http://www.nature.com/nrc/journal/v8/n9/full/nrc2468.html
Hypoxia signalling through mTOR and the unfolded protein response in cancer
Bradly G. Wouters & Marianne Koritzinsky
http://www.nature.com/nrc/journal/v8/n11/full/nrc2501.html
Nutrient sensing: TOR’s Ragtime
Alfred J. Meijer and Patrice Codogno
http://www.nature.com/ncb/journal/v10/n8/full/ncb0808-881.html
Cancer Cell Metabolism: Warburg and Beyond
P.P. Hsu and D.M. Sabatini
http://www.cell.com/content/article/fulltext?uid=PIIS0092867408010660
Autophagy inhibitors deliver a knock-out blow
Richard Robinson
J. Cell Biol. 2008;183 2-3, Published online Oct 6 2008, 10.1083/jcb.1831iti3.
http://www.jcb.org/cgi/content/full/183/1/2-b?etoc
