Apolist – november 2011
Posted by cris on December 1, 2011
——————–
Bcl-2 family
——————–
Glycolysis inhibition targets Mcl-1 to restore sensitivity of lymphoma cells to ABT-737-induced apoptosis
O Meynet, M Bénéteau, M A Jacquin, L A Pradelli, A Cornille, M Carles and J-E Ricci
http://www.nature.com/leu/journal/vaop/ncurrent/full/leu2011327a.html
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
Triona Ni Chonghaile, Kristopher A. Sarosiek, Thanh-Trang Vo, Jeremy A. Ryan, Anupama Tammareddi, Victoria Del Gaizo Moore, Jing Deng, Kenneth C. Anderson, Paul Richardson, Yu-Tzu Tai, Constantine S. Mitsiades, Ursula A. Matulonis, Ronny Drapkin, Richard Stone, Daniel J. DeAngelo, David J. McConkey, Stephen E. Sallan, Lewis Silverman, Michelle S. Hirsch, Daniel Ruben Carrasco, and Anthony Letai
http://www.sciencemag.org/content/334/6059/1129.full
Active Bax and Bak are functional holins
Xiaming Pang, Samir H. Moussa, Natalie M. Targy, Jeffrey L. Bose, Nicholas M. George, Casey Gries, Hernando Lopez, Liqiang Zhang, Kenneth W. Bayles, Ry Young, and Xu Luo
http://genesdev.cshlp.org/cgi/content/abstract/25/21/2278
A natural compound elevates expression of Bim that interacts with Bcl-2 converting the anti-apoptotic protein to a pro-apoptotic Bax-like molecule
Lixia Zhao, Feng He, Haiyang Liu, Yushan Zhu, Weili Tian, Ping Gao, Hongping He, Wen Yue, Xiaobo Lei, Biyun Ni, Xiaohui Wang, Haijing Jin, Xiaojiang Hao, Jialing Lin, and Quan Chen
http://www.jbc.org/cgi/content/abstract/M111.264481v1
Inhibitor of Nrf2 (INrf2 or Keap1) degrades Bcl-xL via Phosphoglycerate mutase 5 and controls cellular apoptosis
Suryakant K. Niture and Anil K. Jaiswal
http://www.jbc.org/cgi/content/abstract/M111.275073v2
Death receptor pathway
———————————-
Nadine Khadra, Laurence Bresson-Bepoldin, Aubin Penna, Benjamin Chaigne-Delalande, Bruno Ségui, Thierry Levade, Anne-Marie Vacher, Josy Reiffers, Thomas Ducret, Jean-François Moreau, Michael D. Cahalan, Pierre Vacher, and Patrick Legembre
http://www.pnas.org/content/108/47/19072.abstract?etoc
Cooperative Phosphorylation of FADD by Aur-A and Plk1 in Response to Taxol Triggers Both Apoptotic and Necrotic Cell Death
Moon-Sun Jang, Su-Jin Lee, Nam Sook Kang, and Eunhee Kim
http://cancerres.aacrjournals.org/cgi/content/abstract/71/23/7207
Oncogenic Ras and B-Raf positively regulates death receptor 5 expression through co-activation of ERK and JNK signaling
You-Take Oh, Ping Yue, Wei Zhou, Justin M. Balko, Esther P. Black, Taofeek K. Owonikoko, Fadlo R. Khuri, and Shi-Yong Sun
http://www.jbc.org/cgi/content/abstract/M111.304006v1
————————————–
Non-apoptotic cell death
————————————–
Caspase 8 inhibits programmed necrosis by processing CYLD.
O’Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R, Green DR, Ting AT.
http://www.nature.com/ncb/journal/vaop/ncurrent/full/ncb2362.html
TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
N Vanlangenakker, M J M Bertrand, P Bogaert, P Vandenabeele and T Vanden Berghe
http://www.nature.com/cddis/journal/v2/n11/full/cddis2011111a.html
CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101
Margot Jak, Gregor G. W. van Bochove, Eric A. Reits, Wouter W. Kallemeijn, Jacqueline M. Tromp, Pablo Umana, Christian Klein, Rene A. W. van Lier, Marinus H. J. van Oers, and Eric Eldering
http://bloodjournal.hematologylibrary.org/cgi/content/abstract/118/19/5178
Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death
Hiroshi Kanda, Tatsushi Igaki, Hideyuki Okano, and Masayuki Miura
http://www.pnas.org/content/108/47/18977.abstract?etoc
Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study
S Shen, O Kepp, M Michaud, I Martins, H Minoux, D Métivier, M C Maiuri, R T Kroemer and G Kroemer
http://www.nature.com/onc/journal/v30/n45/abs/onc2011168a.html
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
Oliver Florey, Sung Eun Kim,1, 2 Cynthia P. Sandoval,3 Cole M. Haynes1, 2 & Michael Overholtzer
http://www.nature.com/ncb/journal/v13/n11/full/ncb2363.html
————————
Miscellaneous
————————
Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α
Inna S. Afonina, Graham A. Tynan, Susan E. Logue, Sean P. Cullen, Michael Bots, Alexander U. Lüthi, Emer P. Reeves, Noel G. McElvaney, Jan P. Medema, Ed C. Lavelle, Seamus J. Martin
http://www.cell.com/molecular-cell/abstract/S1097-2765%2811%2900717-9
Constitutive exposure of phosphatidylserine on viable cells
Katsumori Segawa, Jun Suzuki, and Shigekazu Nagata
http://www.pnas.org/content/108/48/19246.long
Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles
Rostyslav O. Bilyy, Tanya Shkandina, Andriy Tomin, Luis E. Munoz, Sandra Franz, Volodymyr Antonyuk, Yuriy Ya Kit, Matthias Zirngibl, Barbara G. Fuernrohr, Christina Janko, Kirsten Lauber, Martin Schiller, Georg Schett, Rostyslav S. Stoika, and Martin Herrmann
http://www.jbc.org/cgi/content/abstract/M111.273144v1
Polypeptide modulators of card-card-mediated protein-protein interactions
Yadira Palacios-Rodriguez, Guillermo Garcia-Lainez, Monica Sancho, Anna Gortat, Mar Orzaez, and Enrique Perez-Paya
http://www.jbc.org/cgi/content/abstract/M111.255364v1
BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.
Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C.
http://www.ncbi.nlm.nih.gov/pubmed/21926971
——————-
Reviews
——————-
Programmed Cell Death in Animal Development and Disease
Y. Fuchs and H. Steller
http://www.cell.com/abstract/S0092-8674%2811%2901283-9
Programmed necrosis: backup to and competitor with apoptosis in the immune system
Jiahuai Han, Chuan-Qi Zhong and Duan-Wu Zhang
http://www.nature.com/ni/journal/v12/n12/abs/ni.2159.html
Immunology: A heavyweight knocked out
Douglas R. Green
Caspase-1 is one of the main culprits behind sepsis, a form of systemic inflammation.
http://www.nature.com/nature/journal/v479/n7371/full/479048a.html
BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore
Loren D. Walensky, Evripidis Gavathiotis
http://www.sciencedirect.com/science/article/pii/S0968000411001423
—————————————————–
Correspondence / Comments / other
—————————————————–
Staying Alive: Defensive Strategies in the BCL-2 Family Playbook
S.P. Cullen, C.M. Henry, and S.J. Martin
http://www.cell.com/molecular-cell/abstract/S1097-2765%2811%2900847-1
Priming Cancer Cells for Death
John C. Reed
http://www.sciencemag.org/content/334/6059/1075.full
Mcl-1 leves need not be lowered for ABT-263/737-induced apoptosis
R Yamaguchi and G Perkins
http://www.nature.com/cddis/journal/v2/n11/full/cddis2011109a.html
Finding a panacea among combination cancer therapies
by Ryuji Yamaguchi & Guy Perkins
http://cancerres.aacrjournals.org/content/early/2011/11/02/0008-5472.CAN-11-3091.abstract
Cell death: The single-membrane diet
Autophagy proteins function in a non-canonical single-membrane vesicle degradation pathway.
http://www.nature.com/nrm/journal/v12/n12/full/nrm3224.html
Primed for Death
Paula A. Kiberstis
The mitochondrial state of a tumor cell prior to chemotherapy may help determine how well it responds to drug treatment.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/201/ec335
Mcl-1 Reduction Due to Caspase-dependent Cleavage during Endoplasmic Reticulum Stress-induced Apoptosis
Jinsong Hu, Nana Dang, Tusheng Song, and Karin Vanderkerken
http://www.jbc.org/content/286/44/le24.long
Reply to Hu et al.: Mcl-1 Reduction Due to Caspase-dependent Cleavage during Endoplasmic Reticulum Stress-induced Apoptosis
Nobuhiro Morishima, Keiko Nakanishi, and Akihiko Nakano
http://www.jbc.org/content/286/44/le25.full
Profile of Tak Wah Mak
Jennifer Viegas
http://www.pnas.org/content/108/48/19124.full
Snapshot: Mitochondrial Quality Control
D.R. Green and B. van Houten
http://www.sciencedirect.com/science/article/pii/S0092867411012864
International EMBO Molecular Medicine Workshop 2011 on ‘Cell Death and Disease’
A Hague and L S Dickens
http://www.nature.com/cdd/journal/v18/n12/full/cdd2011108a.html
Cell picture show – cell death
http://www.cell.com/Cell_Picture_Show-celldeath
————
————
————
