Apolist – may 2009

Death receptors

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
Z. Jin, Y. Li, R. Pitti, D. Lawrence, V.C. Pham, J.R. Lill, and A. Ashkenazi
http://dx.doi.org/10.1016/j.cell.2009.03.015

Mechanism of procaspase-8 activation by c-FLIPL
Jong W. Yu, Philip D. Jeffrey, and Yigong Shi
http://www.pnas.org/content/106/20/8169.full

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo
Vladislava Juric, Chih-Chiun Chen, and Lester F. Lau
http://mcb.asm.org/cgi/content/abstract/29/12/3266

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis
M Olsson, H Vakifahmetoglu, P M Abruzzo, K Högstrand, A Grandien & B Zhivotovsky
http://www.nature.com/onc/journal/v28/n18/full/onc200936a.html

Akt and 14-3-3 Control a PACS-2 Homeostatic Switch that Integrates Membrane Traffic with TRAIL-Induced Apoptosis
J.E. Aslan, H. You, D.M. Williamson, J. Endig, R.T. Youker, L. Thomas, H. Shu, Y. Du, R.L. Milewski, M.H. Brush, A. Possemato, K. Sprott, H. Fu, K.D. Greis, D.N. Runckel, A. Vogel, and G. Thomas
http://www.cell.com/molecular-cell/abstract/S1097-2765(09)00240-8

Modulation of Caspase Activity Regulates Skeletal Muscle Regeneration and Function in Response to Vasopressin and Tumor Necrosis Factor
Viviana Moresi, Gisela Garcia-Alvarez, Alessandro Pristerà, Emanuele Rizzuto, Maria C. Albertini, Marco Rocchi, Giovanna Marazzi, David Sassoon, Sergio Adamo, Dario Coletti
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005570

BH3

Bcl-2 Proteins EGL-1 and CED-9 Do Not Regulate Mitochondrial Fission or Fusion in Caenorhabditis elegans
D.G. Breckenridge, B.-H. Kang, and D. Xue
http://www.cell.com/current-biology/abstract/S0960-9822%2809%2900825-2

BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK
Emelyn H. Shroff, Colleen M. Snyder, G. R. Scott Budinger, Manu Jain, Teng-Leong Chew, Satya Khuon, Harris Perlman, Navdeep S. Chandel
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005646

Execution of Superoxide-Induced Cell Death by the Proapoptotic Bcl-2-Related Proteins Bid and Bak
Muniswamy Madesh, Wei-Xing Zong, Brian J. Hawkins, Subbiah Ramasamy, Thilagavathi Venkatachalam, Partha Mukhopadhyay, Patrick J. Doonan, Krishna M. Irrinki, Mohanraj Rajesh, Pál Pacher, and Craig B. Thompson
http://mcb.asm.org/cgi/content/abstract/29/11/3099

Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function
I A Ciechomska, G C Goemans, J N Skepper and A M Tolkovsky
http://www.nature.com/onc/journal/v28/n21/full/onc200960a.html

KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis
Chunyan Tian, Guichun Xing, Ping Xie, Kefeng Lu, Jing Nie, Jian Wang, Li Li, Mei Gao, Lingqiang Zhang and Fuchu He
http://www.nature.com/ncb/journal/v11/n5/full/ncb1864.html

Other

The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex
Frédéric Mille, Chantal Thibert, Joanna Fombonne, Nicolas Rama, Catherine Guix, Hideki Hayashi, Véronique Corset, John C. Reed and Patrick Mehlen
http://www.nature.com/ncb/journal/v11/n6/full/ncb1880.html

DeadEasy Caspase: Automatic Counting of Apoptotic Cells in Drosophila
Manuel G. Forero, Jenny A. Pennack, Anabel R. Learte, Alicia Hidalgo
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005441

Apoptosis is not required for mammalian neural tube closure
Valentina Massa, Dawn Savery, Patricia Ybot-Gonzalez, Elisabetta Ferraro, Anthony Rongvaux, Francesco Cecconi, Richard Flavell, Nicholas D. E. Greene, and Andrew J. Copp
http://www.pnas.org/content/106/20/8233.abstract?etoc

The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins
Salah Abu-Hamad, Nir Arbel, Doron Calo, Laetitia Arzoine, Adrian Israelson, Nurit Keinan, Ronit Ben-Romano, Orr Friedman, and Varda Shoshan-Barmatz
http://jcs.biologists.org/cgi/content/abstract/122/11/1906

Stress-dependent chip/DAXX interaction suppresses the p53 apoptotic program
Holly McDonough, Peter C. Charles, Eleanor G. Hilliard, Shu-Bing Qian, Jin-na Min, Andrea L. Portbury, Douglas M. Cyr, and Cam Patterson
http://www.jbc.org/cgi/content/abstract/M109.011767v1

REVIEWS / COMMENTS

Cytoplasmic functions of the tumour suppressor p53
Douglas R. Green and Guido Kroemer
http://www.nature.com/nature/journal/v458/n7242/full/4581118a.html

The CULt of Caspase-8 Ubiquitination
M. Békés and G.S. Salvesen
http://dx.doi.org/10.1016/j.cell.2009.04.052

Of Elections and Cell-Death Decisions
P. Loriaux and A. Hoffmann
http://dx.doi.org/10.1016/j.molcel.2009.05.001

Immunogenic and tolerogenic cell death
Douglas R. Green, Thomas Ferguson, Laurence Zitvogel & Guido Kroemer
http://www.nature.com/nri/journal/v9/n5/abs/nri2545.html

Beclin 1: a BH3-only protein that fails to induce apoptosis
P Boya and G Kroemer
http://www.nature.com/onc/journal/v28/n21/full/onc200983a.html

Human caspases: Activation, specificity and regulation
Cristina Pop and Guy S Salvesen
http://www.jbc.org/cgi/content/abstract/R800084200v1

Hyung Don Ryoo: A healthy career in cellular death
Ruth Williams
http://jcb.rupress.org/cgi/content/full/185/5/758?etoc